Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724740 | 0.81 | HTR2A (0.37) | HTR2AHTR2CHTR2BCHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL9724780 | 0.79 | HTR2A (0.36) | HTR2AHTR2CHTR2BCHRM2CHRM4 | |
| SCHEMBL10586761 | 0.79 | HTR2A (0.36) | HTR2AHTR2CHTR2BCHRM2CHRM4 | |
| SCHEMBL9724718 | 0.78 | HTR2A (0.36) | HTR2AHTR2CHTR2BCHRM2CHRM4 | |
| SCHEMBL10588391 | 0.77 | HTR2A (0.38) | HTR2AHTR2CHTR2BCHRM2CHRM4 | |
| SCHEMBL10586946 | 0.77 | CHRM2 (0.44) | HTR2AHTR2CHTR2BCHRM2CHRM4 | |
| SCHEMBL10518946 | 0.77 | USP7 (0.41) | HTR2AHTR2CHTR2B | |
| SCHEMBL10589178 | 0.76 | HTR2A (0.34) | HTR2AHTR2CHTR2BCHRM2CHRM4 | |
| SCHEMBL10588409 | 0.76 | HTR2A (0.34) | HTR2AHTR2CHTR2BCHRM2CHRM4 | |
| Oxalic Acid SCHEMBL10418895 | 0.71 | CHRM2 (0.41) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322034-A2 | Methyl tetrahydropyridyl oxadiazoles | MERCK SHARP & DOHME LTD. (GB) | 1989-06-28 | — | — | EP | claimed |
| EP-0322034-A2 | Methyl tetrahydropyridyl oxadiazoles | MERCK SHARP & DOHME LTD. (GB) | 1989-06-28 | — | — | EP | disclosed |