Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | HMGCR | P04035 | 2/20 | 0.48 |
| ▸ | DHCR24 | Q15392 | 1/20 | 0.46 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | NPC1L1 | Q9UHC9 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP8B1 | Q9UNU6 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 3/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | OSBP | P22059 | 1/20 | 0.41 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.41 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10588483 | 1.00 | USP2 (0.62) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9766731 | 0.85 | USP2 (0.58) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9464748 | 0.84 | USP2 (0.65) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11490959 | 0.84 | USP2 (0.65) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9464083 | 0.84 | USP2 (0.65) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9353906 | 0.83 | MEN1 (0.43) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8430174 | 0.83 | USP2 (0.66) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11412303 | 0.83 | USP2 (0.63) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11412547 | 0.83 | USP2 (0.63) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9769632 | 0.83 | USP2 (0.63) | USP2MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335106-A2 | Novel intermediates and an improved process for producing the compound (3 beta, 5 alpha)-3-hydroxycholest-8(14)-en-15-one | AMERICAN CYANAMID COMPANY (US) | 1989-10-04 | — | — | EP | claimed |