Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HMGCR | P04035 | 2/20 | 0.40 |
| ▸ | CDC25A | P30304 | 4/20 | 0.39 |
| ▸ | CDC25B | P30305 | 2/20 | 0.38 |
| ▸ | POLA1 | P09884 | 2/20 | 0.37 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.36 |
| ▸ | EBP | Q15125 | 3/20 | 0.35 |
| ▸ | DHCR24 | Q15392 | 2/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.33 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10587792 | 0.87 | MEN1 (0.42) | MEN1USP2ALDH1A1MAPTALOX15 | |
| SCHEMBL10587788 | 0.87 | MEN1 (0.42) | MEN1USP2ALDH1A1MAPTALOX15 | |
| SCHEMBL10424858 | 0.87 | MEN1 (0.42) | MEN1USP2ALDH1A1MAPTALOX15 | |
| SCHEMBL8837048 | 0.87 | MEN1 (0.42) | MEN1USP2ALDH1A1MAPTALOX15 | |
| SCHEMBL9350364 | 0.87 | MEN1 (0.42) | MEN1USP2ALDH1A1MAPTALOX15 | |
| SCHEMBL9164370 | 0.87 | MEN1 (0.42) | MEN1USP2ALDH1A1MAPTALOX15 | |
| SCHEMBL10588487 | 0.83 | USP2 (0.62) | MEN1USP2ALDH1A1MAPTALOX15 | |
| SCHEMBL10588483 | 0.83 | USP2 (0.62) | MEN1USP2ALDH1A1MAPTALOX15 | |
| SCHEMBL10426464 | 0.77 | HMGCR (0.40) | MEN1USP2ALDH1A1MAPTALOX15 | |
| SCHEMBL9769614 | 0.73 | HMGCR (0.46) | MEN1USP2ALDH1A1MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0327119-B1 | Improved process for synthesis of 5-alpha-cholest-8(14)-en-3 beta-ol-15-one and other 15-oxygenated sterols | UNIV RICE WILLIAM M (US) | 1994-09-14 | — | — | EP | disclosed |