Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.51 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12923166 | 0.89 | POLB (0.64) | ALOX15CYP2C19TDP1ALDH1A1SCN5A | |
| SCHEMBL21820780 | 0.86 | CYP2C19 (0.60) | ALOX15TSHRCYP2C19HIF1ATDP1 | |
| SCHEMBL23388356 | 0.84 | CYP2C19 (0.58) | ALOX15TSHRCYP2C19HIF1ATDP1 | |
| SCHEMBL11142972 | 0.84 | ALOX15 (0.58) | ALOX15TSHRCYP2C19HIF1ATDP1 | |
| SCHEMBL6769239 | 0.84 | SMN1; SMN2 (0.59) | ALOX15TSHRCYP2C19HIF1ATDP1 | |
| SCHEMBL10392123 | 0.84 | ALOX15 (0.58) | ALOX15TSHRCYP2C19HIF1ATDP1 | |
| SCHEMBL18415577 | 0.83 | HTT (0.58) | ALOX15TSHRCYP2C19HIF1ATDP1 | |
| SCHEMBL12933284 | 0.81 | POLB (0.60) | ALOX15TSHRCYP2C19HIF1ATDP1 | |
| SCHEMBL27734228 | 0.81 | SMN1; SMN2 (0.57) | ALOX15TSHRCYP2C19HIF1ATDP1 | |
| SCHEMBL28264607 | 0.81 | ALOX15 (0.55) | ALOX15TSHRCYP2C19HIF1ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0340198-A1 | Immunoassay for the detection of alpha-haloacetamides | Monsanto Company (US) | 1989-11-02 | — | — | EP | disclosed |