SCHEMBL10588673

SCHEMBL10588673

CCC=Cc1nc(Cl)c(C=O)[nH]1

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TYMP P19971 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10588663 1.00 TYMP (0.37) TYMP
SCHEMBL3027900 0.71 GAA (0.38)
SCHEMBL2906454 0.68
SCHEMBL895 0.68 GLA (0.37) TYMP
SCHEMBL1256378 0.67 KDM4C (0.35)
SCHEMBL3103844 0.66
SCHEMBL710 0.66 ALDH1A1 (0.40) TYMP
SCHEMBL9468148 0.66
SCHEMBL10588667 0.66
SCHEMBL16404872 0.63 TOP2A (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0324377-A2 Angiotensin II receptor blocking imidazoles and combinations thereof with diuretics and NSaids E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-07-19 EP disclosed