Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | MMP12 | P39900 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9152342 | 0.80 | HTR6 (0.42) | HTR6L3MBTL1KMT2AMEN1POLB | |
| SCHEMBL7365219 | 0.79 | HTR6 (0.41) | HTR6L3MBTL1KMT2AMEN1POLB | |
| SCHEMBL8653117 | 0.76 | HTR6 (0.58) | HTR6SMN1; SMN2LMNATSHRMMP1 | |
| SCHEMBL10727900 | 0.74 | HTR6 (0.56) | HTR6SMN1; SMN2LMNATSHRL3MBTL1 | |
| SCHEMBL29210114 | 0.69 | NPC1 (0.60) | HTR6SMN1; SMN2L3MBTL1KMT2AMEN1 | |
| SCHEMBL30901411 | 0.69 | NPC1 (0.60) | HTR6SMN1; SMN2L3MBTL1KMT2AMEN1 | |
| SCHEMBL699183 | 0.69 | HTR6 (0.50) | HTR6SMN1; SMN2LMNATSHRL3MBTL1 | |
| SCHEMBL31000980 | 0.69 | GAA (0.68) | HTR6SMN1; SMN2L3MBTL1KMT2AMEN1 | |
| SCHEMBL11853033 | 0.69 | GAA (0.68) | HTR6SMN1; SMN2L3MBTL1KMT2AMEN1 | |
| SCHEMBL7446867 | 0.68 | SLC1A3 (0.44) | HTR6L3MBTL1KMT2AMEN1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0323802-A2 | Monoclonal antibodies against, and cell surface antigen of, lung carcinoma | SANDOZ AG (CH) | 1989-07-12 | — | — | EP | disclosed |