Ethylbenzene

Ethylbenzene

SCHEMBL10592575

CCc1ccccc1.N.[CaH2]

nearest known ligand 0.88

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.88
CALM1 P0DP23 1/20 0.47
ALDH1A1 P00352 4/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2A6 P11509 1/20 0.44
TSHR P16473 3/20 0.43
IDO1 P14902 1/20 0.43
LOXL2 Q9Y4K0 1/20 0.43
TRPA1 O75762 1/20 0.43
RAB9A P51151 2/20 0.42
POLB P06746 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
KDM4E B2RXH2 3/20 0.42
TDP1 Q9NUW8 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
CYP3A4 P08684 1/20 0.42
MAPT P10636 1/20 0.42
NPC1 O15118 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylbenzene SCHEMBL57658 0.97
Ethylbenzene SCHEMBL7547889 0.97 TP53 (0.93) TP53CALM1ALDH1A1CYP1A2CYP2A6
Ethylbenzene SCHEMBL25237466 0.94 TP53 (0.88) TP53CALM1ALDH1A1CYP1A2CYP2A6
Ethylbenzene SCHEMBL246705 0.94 TP53 (0.88) TP53CALM1ALDH1A1CYP1A2CYP2A6
Ethylbenzene SCHEMBL11703785 0.94 TP53 (0.88) TP53CALM1ALDH1A1CYP1A2CYP2A6
Ethylbenzene SCHEMBL27455702 0.94 TP53 (0.88) TP53CALM1ALDH1A1CYP1A2CYP2A6
Ethylbenzene SCHEMBL11223212 0.94 TP53 (1.00) TP53CALM1ALDH1A1CYP1A2CYP2A6
Ethylbenzene SCHEMBL3987542 0.94 TP53 (1.00) TP53CALM1ALDH1A1CYP1A2CYP2A6
Ethylbenzene SCHEMBL7458207 0.94 TP53 (1.00) TP53CALM1ALDH1A1CYP1A2CYP2A6
Ethylbenzene SCHEMBL1332452 0.94

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4797410-A CALCIUM CHANNEL BLOCKING COMPOUNDS MILES INC. (US) 1989-01-10 US claimed