SCHEMBL105928

SCHEMBL105928

O=C(O)c1ccc2[nH]ccc2c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.72
ALDH1A1 P00352 1/20 0.72
HPGD P15428 1/20 0.72
ENPP2 Q13822 1/20 0.72
HSD17B10 Q99714 1/20 0.72
CTNNB1 P35222 5/20 0.63
WNT3A P56704 5/20 0.63
F2 P00734 1/20 0.59
RAB9A P51151 3/20 0.56
MAPT P10636 2/20 0.56
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2C19 P33261 1/20 0.56
USP2 O75604 1/20 0.53
GAA P10253 1/20 0.53
ALOX15 P16050 1/20 0.53
RAD51 Q06609 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
NPC1 O15118 2/20 0.53
TUBB4A P04350 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL698541 0.98 KDM4E (0.70) KDM4EALDH1A1HPGDENPP2HSD17B10
Bromide SCHEMBL6614789 0.98 KDM4E (0.70) KDM4EALDH1A1HPGDENPP2HSD17B10
Formaldehyde SCHEMBL27620564 0.96 KDM4E (0.68) KDM4EALDH1A1HPGDENPP2HSD17B10
Isopropyl Alcohol SCHEMBL28872249 0.91 KDM4E (0.62) KDM4EALDH1A1HPGDENPP2HSD17B10
Trifluoroacetic Acid SCHEMBL27739600 0.90 KDM4E (0.60) KDM4EALDH1A1HPGDENPP2HSD17B10
SCHEMBL4592729 0.88 KDM4E (0.63) KDM4EALDH1A1HPGDENPP2HSD17B10
SCHEMBL5424831 0.86 KDM4E (0.55) KDM4EALDH1A1HPGDENPP2HSD17B10
SCHEMBL27594531 0.86 TUBB4A (0.67) KDM4EALDH1A1HPGDENPP2HSD17B10
SCHEMBL27583671 0.85 NPC1 (0.66) KDM4EALDH1A1HPGDENPP2HSD17B10
SCHEMBL4591385 0.85 CTNNB1 (0.59) KDM4EALDH1A1HPGDENPP2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2535 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025085689-A1 EXTRACELLULAR SMALL MOLECULE ACTIVATORS TARGETING BESTROPHIN CHANNELS FOR DISEASE TREATMENT THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2025-04-24 WO claimed
CN-119822483-A Method for degrading perfluorinated compounds in sludge 广东工业大学 2025-04-15 CN claimed
CN-119819370-A Preparation method of photocatalytic degradation material for treating acid chrome blue K sewage 北方工业大学 2025-04-15 CN claimed
CN-115920673-B High-flux aromatic polyamide reverse osmosis membrane and preparation method thereof 万华化学集团股份有限公司 2025-02-18 CN claimed
CN-118994223-A Aluminum oxide nanotube crystalline material and preparation method and application thereof 中国科学院福建物质结构研究所 2024-11-22 CN claimed
US-20240270748-A1 TRICYCLIC HETEROCYCLES MERCK PATENT GMBH (DE) 2024-08-15 US claimed
CN-113874361-B Compound with anticancer activity and preparation method thereof 医药生命融合研究团 2024-07-12 CN claimed
CN-115015460-B Method for identifying cordyceps sinensis producing area by using wide-range targeted metabonomics technology 中国检验检疫科学研究院 2024-05-03 CN claimed
CN-117362712-A Preparation method of biodegradable biomass multifunctional antibacterial packaging film 陕西科技大学 2024-01-09 CN claimed
CN-114933724-B Preparation method of nonionic cellulose/polycaprolactone-based antibacterial film 陕西科技大学 2023-09-22 CN claimed
WO-2001055107-A2 AROMATIC AMINES AND AMIDES ACTING ON THE MELANOCORTIN RECEPTORS MELACURE THERAPEUTICS AB (SE) 2001-08-02 WO claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
EP-0673782-B1 Recording sheets containing pyrrole, pyrrolidine, pyridine, piperidine, homopiperidine, quinoline, isoquinoline, quinuclidine, indole, and indazole compounds XEROX CORP (US) 2000-06-14 EP claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
EP-0673782-A2 Recording sheets containing pyrrole, pyrrolidine, pyridine, piperidine, homopiperidine, quinoline, isoquinoline, quinuclidine, indole, and indazole compounds XEROX CORPORATION (US) 1995-09-27 EP claimed
WO-1995006825-A1 LOW FRICTION DEVICES BRITISH TECHNOLOGY GROUP LIMITED (GB) 1995-03-09 WO claimed