⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8741525 | 1.00 | — | — | |
| SCHEMBL1061644 | 0.80 | — | — | |
| SCHEMBL887785 | 0.77 | TSHR (0.30) | — | |
| SCHEMBL1060663 | 0.77 | TSHR (0.30) | — | |
| SCHEMBL10632508 | 0.74 | — | — | |
| SCHEMBL2953096 | 0.72 | — | — | |
| SCHEMBL25408699 | 0.68 | — | — | |
| SCHEMBL13086080 | 0.68 | — | — | |
| SCHEMBL25146 | 0.68 | — | — | |
| SCHEMBL2384813 | 0.68 | TSHR (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2647713-B1 | MODIFIED SINGLE-STRAND POLYNUCLEOTIDE | DAIICHI SANKYO CO LTD (JP) | 2018-02-21 | — | — | EP | claimed |
| US-8987226-B2 | Modified single-stranded polynucleotides | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-03-24 | — | — | US | claimed |
| EP-2647713-A1 | MODIFIED SINGLE-STRAND POLYNUCLEOTIDE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-10-09 | — | — | EP | claimed |
| US-20130253038-A1 | Modified Single-Stranded Polynucleotide | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-09-26 | — | — | US | claimed |
| EP-0684954-B1 | NUCLEIC ACID PROBES CHEMICALLY 5'(OH)- AND/OR 3'(OH)-MODIFIED FOR INSERTING ONE OR MORE NON-RADIOACTIVE LABELING ELEMENTS THEREAT, AND METHOD FOR PREPARING SAME | WALLONE REGION (BE) | 1998-07-22 | — | — | EP | claimed |
| EP-0684954-A1 | NUCLEIC ACID PROBES CHEMICALLY 5'(OH)- AND/OR 3'(OH)-MODIFIED FOR INSERTING ONE OR MORE NON-RADIOACTIVE LABELING ELEMENTS THEREAT, AND METHOD FOR PREPARING SAME | LA REGION WALLONNE (BE) | 1995-12-06 | — | — | EP | claimed |
| WO-1994019364-A2 | NUCLEIC ACID PROBES CHEMICALLY 5'(OH)- AND/OR 3'(OH)-MODIFIED FOR INSERTING ONE OR MORE NON-RADIOACTIVE LABELING ELEMENTS THEREAT, AND METHOD FOR PREPARING SAME | LA REGION WALLONNE (BE) | 1994-09-01 | — | — | WO | claimed |
| US-5218102-A | Easily synthesized, hybridize well with target sequences | IMPROBIO (BE) | 1993-06-08 | — | — | US | claimed |
| WO-2025264952-A2 | NOVEL RNA THERAPEUTICS AND USES THEREOF | ELI LILLY AND COMPANY (US) | 2025-12-26 | — | — | WO | disclosed |
| WO-2025063239-A1 | SIRNA CAPABLE OF SUPPRESSING EXPRESSION OF α-SYNUCLEIN | 第一三共株式会社 | 2025-03-27 | — | — | WO | disclosed |
| WO-2025063238-A1 | SIRNA FOR SUPPRESSING EXPRESSION OF PHOSPHOLAMBAN | 第一三共株式会社 | 2025-03-27 | — | — | WO | disclosed |
| EP-4373829-A1 | PROCESS FOR PREPARATION OF TARGETING LIGANDS | Janssen Pharmaceuticals, Inc. (US) | 2024-05-29 | — | — | EP | disclosed |
| EP-4153604-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | Wave Life Sciences Ltd. (SG) | 2023-03-29 | — | — | EP | disclosed |
| WO-2023002452-A1 | PROCESS FOR PREPARATION OF TARGETING LIGANDS | Janssen Pharmaceuticals, Inc. (US) | 2023-01-26 | — | — | WO | disclosed |
| US-5082934-A | COUMARIN DERIVATIVES FOR USE AS NUCLEOTIDE CROSSLINKING REAGENTS | NAXCOR (US) | 1992-01-21 | — | — | US | disclosed |
| US-5013830-A | Genetic engineering | AJINOMOTO CO., INC. (JP) | 1991-05-07 | — | — | US | disclosed |
| WO-1990012020-A1 | COUMARIN DERIVATIVES FOR USE AS NUCLEOTIDE CROSSLINKING REAGENTS | NAXCOR (US) | 1990-10-18 | — | — | WO | disclosed |
| EP-0334694-A1 | Nucleic acid probes with non-radioactive labels, and preparation processes | LA REGION WALLONNE (BE) | 1989-09-27 | — | — | EP | disclosed |
| EP-0260032-A2 | Compounds for the cleavage at a specific position of RNA, oligomers employed for the formation of said compounds, and starting materials for the synthesis of said oligomers | AJINOMOTO CO., INC. (JP) | 1988-03-16 | — | — | EP | disclosed |
| EP-0196101-A2 | Purification of synthetic oligomers | CHIRON CORPORATION (US) | 1986-10-01 | — | — | EP | disclosed |