SCHEMBL25146

SCHEMBL25146

COP(Cl)N(C(C)C)C(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL272195 0.84
SCHEMBL9843077 0.80
SCHEMBL18506536 0.77
SCHEMBL14822541 0.77
SCHEMBL11199860 0.73
SCHEMBL1391357 0.73
SCHEMBL1117784 0.69
SCHEMBL1146068 0.69
SCHEMBL10716728 0.69
SCHEMBL16018282 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 277 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2647713-B1 MODIFIED SINGLE-STRAND POLYNUCLEOTIDE DAIICHI SANKYO CO LTD (JP) 2018-02-21 EP claimed
US-8987226-B2 Modified single-stranded polynucleotides DAIICHI SANKYO COMPANY, LIMITED (JP) 2015-03-24 US claimed
EP-2647713-A1 MODIFIED SINGLE-STRAND POLYNUCLEOTIDE DAIICHI SANKYO COMPANY, LIMITED (JP) 2013-10-09 EP claimed
US-20130253038-A1 Modified Single-Stranded Polynucleotide DAIICHI SANKYO COMPANY, LIMITED (JP) 2013-09-26 US claimed
EP-0090789-A1 Chemical DNA synthesis MONSANTO COMPANY (US) 1983-10-05 EP claimed
JP-1250393-A None JP disclosed
US-12453779-B2 Chemoselective thiol-conjugation with alkene or alkyne-phosphonothiolates and -phosphonates FORSCHUNGSVERBUND BERLIN E.V. (DE) 2025-10-28 US disclosed
EP-4628583-A1 BICYCLIC ABASIC NUCLEIC ACID ANALOGS AND OLIGOMERIC COMPOUNDS PREPARED THEREFROM Shanghai Argo Biopharmaceutical Co., Ltd. (CN) 2025-10-08 EP disclosed
US-20250243540-A1 PROBE RELATED REAGENTS AND METHODS BRENTANO BIOTECHNOLOGY ASSOCIATES (US) 2025-07-31 US disclosed
WO-2025063238-A1 SIRNA FOR SUPPRESSING EXPRESSION OF PHOSPHOLAMBAN 第一三共株式会社 2025-03-27 WO disclosed
WO-2025063239-A1 SIRNA CAPABLE OF SUPPRESSING EXPRESSION OF α-SYNUCLEIN 第一三共株式会社 2025-03-27 WO disclosed
EP-3862431-B1 METHOD FOR PRODUCING HAIRPIN SINGLE-STRAND RNA MOLECULES TORAY INDUSTRIES (JP) 2024-06-26 EP disclosed
EP-0210449-A2 Prolonged chemiluminescence MILES INC. (US) 1987-02-04 EP disclosed
EP-0202758-A1 Hybridization method and probes therefor ZENECA LIMITED (GB) 1986-11-26 EP disclosed
EP-0198207-A1 Specific iodination of nucleic acid MOLECULAR DIAGNOSTICS, INC. (US) 1986-10-22 EP disclosed
EP-0194545-A2 Labelling of oligonucleotides MOLECULAR DIAGNOSTICS, INC. (US) 1986-09-17 EP disclosed
EP-0192197-A2 Fast and specific immobilization of nucleic acids to solid supports MOLECULAR DIAGNOSTICS, INC. (US) 1986-08-27 EP disclosed
EP-0191659-A1 Derivatives of adenosine nucleosides, their preparation and their biological use INSTITUT PASTEUR (FR) 1986-08-20 EP disclosed
EP-0144386-A1 NOVEL PREPARATION OF NUCLEOSIDE PHOSPHORAMIDITE INTERMEDIATES. BECKMAN INSTRUMENTS INC (US) 1985-06-19 EP disclosed
WO-1984004749-A1 NOVEL PREPARATION OF NUCLEOSIDE PHOSPHORAMIDITE INTERMEDIATES BECKMAN INSTRUMENTS INC (US) 1984-12-06 WO disclosed