SCHEMBL10595168

SCHEMBL10595168

CCOC(=O)c1nsc(C(C)=O)c1S(=O)(=O)NC(=O)Nc1cc(OC)cc(OC)n1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 4/20 0.42
CREBBP Q92793 1/20 0.41
ALDH1A1 P00352 5/20 0.38
KDM4E B2RXH2 2/20 0.38
MAPT P10636 2/20 0.38
POLB P06746 1/20 0.36
LMNA P02545 1/20 0.36
GAA P10253 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TSHR P16473 1/20 0.34
ADORA3 P0DMS8 1/20 0.33
NPC1 O15118 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
JAK3 P52333 1/20 0.33
CYP3A4 P08684 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8563557 0.74 FBP1 (0.41) FBP1CREBBPALDH1A1KDM4EMAPT
SCHEMBL9061711 0.73 FBP1 (0.42) FBP1CREBBPALDH1A1KDM4EMAPT
SCHEMBL27313081 0.73 FBP1 (0.41) FBP1CREBBPALDH1A1KDM4EMAPT
SCHEMBL8703666 0.73 FBP1 (0.41) FBP1CREBBPALDH1A1KDM4EMAPT
SCHEMBL27399039 0.71 FBP1 (0.41) FBP1CREBBPPOLBGAASMN1; SMN2
SCHEMBL27681797 0.70 FBP1 (0.39) FBP1CREBBPALDH1A1MAPTPOLB
SCHEMBL27500934 0.69 RXFP1 (0.45) FBP1CREBBPALDH1A1KDM4EMAPT
SCHEMBL8563567 0.69 MAPT (0.41) FBP1CREBBPALDH1A1KDM4EMAPT
SCHEMBL27614193 0.68 MEN1 (0.48) FBP1CREBBPALDH1A1KDM4EMAPT
SCHEMBL4451216 0.67 FBP1 (0.41) FBP1CREBBPALDH1A1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-1249773-A None JP disclosed
JP-H01249773-A ISOTHIAZOLESULFONAMIDE DERIVATIVE AND SELECTIVE HERBICIDE NISSAN CHEM IND LTD 1989-10-05 JP disclosed