SCHEMBL10595181

SCHEMBL10595181

CCOC(=O)CC(C)(OCC)OCC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.48
MGAM O43451 1/20 0.48
SI P14410 1/20 0.48
MGAM2 Q2M2H8 1/20 0.48
ALDH1A1 P00352 3/20 0.44
TRPA1 O75762 1/20 0.44
CYP1A2 P05177 1/20 0.39
LMNA P02545 1/20 0.39
HSD17B10 Q99714 1/20 0.39
GSK3A P49840 1/20 0.38
GSK3B P49841 1/20 0.38
HSD11B1 P28845 1/20 0.38
ALOX15 P16050 1/20 0.37
SOAT1 P35610 1/20 0.37
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
CYP4F2 P78329 2/20 0.33
CYP4A11 Q02928 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13502971 0.82 MGAM (0.32) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL16573007 0.82 GAA (0.48) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL7199767 0.82 GAA (0.48) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL407625 0.79 GAA (0.50) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL6650053 0.78 CYP1A2 (0.45) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL23007 0.78 GAA (0.44) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL915738 0.78 TSHR (0.48) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL21052480 0.78 GAA (0.55) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL798062 0.78 GAA (0.55) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL232993 0.78 GAA (0.55) GAAMGAMSIMGAM2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112159358-B Preparation method of oxarogeli intermediate 上海朴颐化学科技有限公司 2023-08-18 CN disclosed
CN-112159358-A Preparation method of oxalagogri intermediate 上海朴颐化学科技有限公司 2021-01-01 CN disclosed
CN-108017523-A A kind of method for preparing the chloro- 3,3,3- trifluoroacetones of 1- 浙江蓝天环保高科技股份有限公司 2018-05-11 CN disclosed
CN-102412416-A Nonaqueous electrolyte and nonaqueous electrolyte battery SONY CORP 2012-04-11 CN disclosed
EP-0346852-A2 Process for producing 4-chloro-3-alkoxybut-2E-ene acid alkyl esters LONZA AG (CH) 1989-12-20 EP disclosed
US-4504422-A FROM OLEFIN, ALCOHOL, PLATINUM GROUP CATALYST, NITRITE UBE INDUSTRIES, LTD. (JP) 1985-03-12 US disclosed
US-4501705-A REACT OLEFIN AND ALCOHOL IN PRESENCE OF ESTER NITRITE, PLATINUM GROUP CATALYSTS AND COPPER HALIDE UBE INDUSTRIES, LTD. (JP) 1985-02-26 US disclosed
EP-0055108-B1 PROCESS FOR PRODUCING AN ACETAL UBE INDUSTRIES, LTD. (JP) 1984-09-05 EP disclosed
US-4198343-A Method of preparing dihalogen vinyl cyclopropanecarboxylic acid esters DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1980-04-15 US disclosed
US-4198342-A Method of preparing dihalogen vinyl cyclopropanecarboxylic acid esters DYNAMIT NOBEL ATKIENGESELLSCHAFT (DE) 1980-04-15 US disclosed
US-4198341-A 2,5,5-Trimethyl-3-carbalkoxy-4(β,β-dihalovinyl)-4,5-dihydrofurans DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1980-04-15 US disclosed
US-4180446-A Method of preparing dihalogen vinyl cyclopropanecarboxylic acid esters DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1979-12-25 US disclosed