SCHEMBL798062

SCHEMBL798062

CCOC(=O)CC(C)(C)C

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.55
MGAM O43451 1/20 0.55
SI P14410 1/20 0.55
MGAM2 Q2M2H8 1/20 0.55
ALDH1A1 P00352 4/20 0.50
TRPA1 O75762 1/20 0.50
LMNA P02545 2/20 0.43
HSD17B10 Q99714 1/20 0.43
CYP1A2 P05177 1/20 0.43
GSK3A P49840 1/20 0.42
GSK3B P49841 1/20 0.42
ALOX15 P16050 1/20 0.42
SOAT1 P35610 1/20 0.42
HSD11B1 P28845 1/20 0.41
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
MMP8 P22894 1/20 0.38
MIF P14174 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12933286 0.84 HSD11B1 (0.50) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL21052480 0.84 GAA (0.55) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL232993 0.84 GAA (0.55) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL927785 0.82 GAA (0.52) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL7563037 0.82 GAA (0.52) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL11861490 0.82 GAA (0.52) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL21299 0.81 GAA (0.58) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL13251257 0.81 GAA (0.46) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL15694063 0.81 DGKA (0.39) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL23779364 0.80 GAA (0.50) GAAMGAMSIMGAM2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 301 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3647312-B1 CRYSTAL FORM OF DEUTERATED AZD9291, PREPARATION METHOD THEREFOR, AND USE THEREOF TYK MEDICINES INC (CN) 2023-05-10 EP claimed
US-7795255-B2 Rigidified compounds for modulating heparanase activity INSIGHT BIOPHARMACEUTICALS LTD. (IL) 2010-09-14 US claimed
EP-4583177-A1 METHOD OF MANUFACTURING ELECTRODE, COMPOSITE ELECTRODE, ELECTROCHEMICAL ELEMENT, AND APPARATUS FOR MANUFACTURING ELECTRODE Ricoh Company, Ltd. (JP) 2025-07-09 EP disclosed
WO-2025062334-A1 4-((5-(3-(4-(PYRIDIN-2-YL)CYCLOPENTYL)-1 H-PYRAZOL-3-YL)AMINO)-BENZENESULFONAMIDE DERIVATIVES AND SIMILAR COMPOUNDS AS CDK INHIBITORS FOR THE TREATMENT OF CANCER BEIGENE SWITZERLAND GMBH (CH) 2025-03-27 WO disclosed
US-12173403-B2 Group 6 transition metal-containing compositions for vapor deposition of group 6 transition metal-containing films L'Air Liquide, Société Anonyme pour l'Etude et l'Exploitation des Procédés Georges Claude (FR) 2024-12-24 US disclosed
US-12043674-B2 Synthetic cyclic peptides and methods of preparation and use thereof AUBURN UNIVERSITY (US) 2024-07-23 US disclosed
US-20240207353-A1 USE OF PEPTIDE AMIDE COMPOUND IN PREPARATION OF DRUG FOR TREATING PRURITUS XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) 2024-06-27 US disclosed
EP-4362128-A1 LIQUID COMPOSITION, METHOD FOR PRODUCING LIQUID COMPOSITION, ELECTRODE, ELECTRODE PRODUCTION APPARATUS, AND METHOD FOR PRODUCING ELECTRODE Ricoh Company, Ltd. (JP) 2024-05-01 EP disclosed
US-20240067641-A1 INHIBITORS OF TRIM33 AND METHODS OF USE DANA-FARBER CANCER INSTITUTE, INC. (US) 2024-02-29 US disclosed
US-20230357165-A1 QUINAZOLINONES DERIVATIVES FOR TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE, PREPARATION AND USE THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2023-11-09 US disclosed
EP-3356345-B1 HETEROARYL DERIVATIVES AS SEPIAPTERIN REDUCTASE INHIBITORS MAX PLANCK GESELLSCHAFT (DE) 2023-11-08 EP disclosed
US-5936132-A Alkene intermediates and synthesis thereof MATSUMOTO MASAKATSU (JP) 1999-08-10 US disclosed
EP-0885891-A1 ISOXAZOLE DERIVATIVES SANKYO COMPANY LIMITED (JP) 1998-12-23 EP disclosed
US-5698727-A 1,2-dioxetane derivatives, intermediates for syntheses thereof and methods of producing the intermediates MATSUMOTO MASAKATSU (JP) 1997-12-16 US disclosed
US-5650525-A 1,2-dioxetane derivatives, intermediates for syntheses thereof and methods of producing the intermediates TOSOH CORPORATION (JP) 1997-07-22 US disclosed
EP-0671395-A1 1,2-Dioxetane derivatives, intermediates for syntheses thereof and methods of producing the intermediates Matsumoto, Masakatsu (JP) 1995-09-13 EP disclosed
EP-0605686-A1 EMULSION POLYMERS FOR USE IN HAIR FIXATIVES National Starch and Chemical Investment Holding Corporation (US) 1994-07-13 EP disclosed
CN-1078475-A A kind of improved with the steroid 3-halogen-3 that replaces, the 5-diene derivatives is converted into the steroid 3 of replacement, the method for 5-diene-3-carboxylic acid derivative and used intermediate SMITHKLINE BEECHAM CORP (US) 1993-11-17 CN disclosed
US-5011947-A Enzyme inhibitors for cholesterol biosythesis BRISTOL-MYERS (US) 1991-04-30 US disclosed
EP-0295839-A2 Pyrimidine derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-12-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357165-A1 QUINAZOLINONES DERIVATIVES FOR TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE, PREPARATION AND USE THEREOF ATG7, GOT1, LIPC GAA 313/4885MGAM 1584/4885SI 2362/4885
US-12043674-B2 Synthetic cyclic peptides and methods of preparation and use thereof VIP, PTMS, IAPP GAA 4203/4885MGAM 4724/4885SI 756/4885
US-20240067641-A1 INHIBITORS OF TRIM33 AND METHODS OF USE TRIM33, TRIM28, TRIM4 GAA 1769/4885MGAM 3635/4885SI 3410/4885
US-20240207353-A1 USE OF PEPTIDE AMIDE COMPOUND IN PREPARATION OF DRUG FOR TREATING PRURITUS VIP, GRPR, ITCH GAA 3565/4885MGAM 2815/4885SI 88/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.