Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | F3 | P13726 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10594235 | 0.91 | ALDH1A1 (0.47) | ALDH1A1KMT2AF2HPGDTP53 | |
| SCHEMBL10344654 | 0.90 | ALDH1A1 (0.46) | ALDH1A1KMT2AF2HPGDTP53 | |
| SCHEMBL10967915 | 0.88 | NOTUM (0.47) | ALDH1A1TP53SMN1; SMN2PBRM1MAPT | |
| SCHEMBL10344537 | 0.87 | PBRM1 (0.63) | ALDH1A1KMT2AF2HPGDTP53 | |
| SCHEMBL10508900 | 0.86 | ALDH1A1 (0.49) | ALDH1A1KMT2AF2HPGDTP53 | |
| SCHEMBL17554048 | 0.85 | ALDH1A1 (0.67) | ALDH1A1KMT2AF2HPGDTP53 | |
| SCHEMBL10962479 | 0.84 | KMT2A (0.46) | ALDH1A1KMT2AF2HPGDTP53 | |
| SCHEMBL10834685 | 0.83 | ALDH1A1 (0.71) | ALDH1A1KMT2AF2HPGDTP53 | |
| SCHEMBL7186075 | 0.81 | F7 (0.54) | ALDH1A1KMT2AF2HPGDPBRM1 | |
| SCHEMBL10344798 | 0.81 | HPN (0.57) | ALDH1A1KMT2AF2HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0136646-B1 | PROCESS FOR THE PREPARATION OF 5-FLUOR-4H-3,1-BENZOXAZIN-4-ONES | BASF Aktiengesellschaft (DE) | 1989-01-25 | — | — | EP | disclosed |
| US-4562254-A | Preparation of 5-fluoro-2-phenyl-4H-3,1-benzoxazin-4-ones | BASF AKTIENGESELLSCHAFT (DE) | 1985-12-31 | — | — | US | disclosed |