SCHEMBL10595641

SCHEMBL10595641

CCCCCC(Oc1ccc(N)cc1)Oc1ccc(N)cc1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 5/20 0.44
TSHR P16473 4/20 0.44
SLC2A1 P11166 2/20 0.41
CYP3A4 P08684 3/20 0.41
LMNA P02545 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
PDE4D Q08499 1/20 0.41
ALDH1A1 P00352 3/20 0.39
MAPT P10636 3/20 0.39
NPC1 O15118 3/20 0.39
RAB9A P51151 3/20 0.39
MAPK1 P28482 1/20 0.39
CSNK1E P49674 1/20 0.38
KDM4E B2RXH2 1/20 0.37
TEAD4 Q15561 1/20 0.35
OPRM1 P35372 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12112116 0.98 SLC2A1 (0.44) TDP1TSHRSLC2A1CYP3A4LMNA
SCHEMBL29931157 0.98 SLC2A1 (0.44) TDP1TSHRSLC2A1CYP3A4LMNA
SCHEMBL7908097 0.98 SLC2A1 (0.44) TDP1TSHRSLC2A1CYP3A4LMNA
SCHEMBL10596695 0.98 SLC2A1 (0.44) TDP1TSHRSLC2A1CYP3A4LMNA
SCHEMBL15939864 0.98 SLC2A1 (0.44) TDP1TSHRSLC2A1CYP3A4LMNA
SCHEMBL25283342 0.98 SLC2A1 (0.44) TDP1TSHRSLC2A1CYP3A4LMNA
SCHEMBL10597474 0.98 SLC2A1 (0.44) TDP1TSHRSLC2A1CYP3A4LMNA
SCHEMBL2535207 0.94 TDP1 (0.45) TDP1TSHRSLC2A1CYP3A4LMNA
SCHEMBL27140504 0.93 ALDH1A1 (0.45) TDP1TSHRSLC2A1CYP3A4ALDH1A1
SCHEMBL21693990 0.88 TSHR (0.54) TDP1TSHRCYP3A4LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111448510-B Liquid crystal aligning agent, liquid crystal alignment film, liquid crystal element, and method for producing liquid crystal element JSR株式会社 2023-03-14 CN disclosed
CN-111433665-B Liquid crystal aligning agent, liquid crystal alignment film, liquid crystal element, and method for producing liquid crystal element JSR株式会社 2023-02-28 CN disclosed
CN-114058382-A Liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal element JSR株式会社 2022-02-18 CN disclosed
CN-111448510-A Liquid crystal aligning agent, liquid crystal alignment film, liquid crystal element, and method for producing liquid crystal element JSR株式会社 2020-07-24 CN disclosed
CN-111433665-A Liquid crystal aligning agent, liquid crystal alignment film, liquid crystal element, and method for producing liquid crystal element JSR株式会社 2020-07-17 CN disclosed
CN-105733610-B Composition containing polyamic acid polymer, liquid crystal aligning agent, liquid crystal aligning film and liquid crystal display element JSR株式会社 2019-12-17 CN disclosed
US-20140226116-A1 LIQUID CRYSTAL DISPLAY AND METHOD FOR PRODUCING LIQUID CRYSTAL DISPLAY JSR CORPORATION (JP) 2014-08-14 US disclosed
EP-0322943-A2 Thermotropic copolyazomethines and process for preparing them ENIRICERCHE S.p.A. (IT) 1989-07-05 EP disclosed