Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.61 |
| ▸ | MIF | P14174 | 2/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | ACP3 | P15309 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23507031 | 0.86 | TAAR1 (0.45) | TAAR1MIFIDO1HTR2AHTR2B | |
| Formaldehyde SCHEMBL28263667 | 0.83 | TAAR1 (0.57) | TAAR1MIFIDO1HTR2AHTR2B | |
| SCHEMBL66607 | 0.82 | TAAR1 (0.61) | TAAR1MIFIDO1HTR2AHTR2B | |
| SCHEMBL11188459 | 0.82 | TAAR1 (0.61) | TAAR1MIFIDO1HTR2AHTR2B | |
| SCHEMBL16167473 | 0.82 | TAAR1 (0.40) | TAAR1MIFHTR2AHTR2BHTR2C | |
| SCHEMBL1330066 | 0.81 | TAAR1 (0.55) | TAAR1MIFIDO1HTR2AHTR2B | |
| SCHEMBL1046631 | 0.79 | TAAR1 (0.67) | TAAR1MIFIDO1HTR2AHTR2B | |
| SCHEMBL8507257 | 0.79 | TAAR1 (0.57) | TAAR1MIFIDO1HTR2AHTR2B | |
| SCHEMBL26028493 | 0.79 | SCN8A (0.53) | TAAR1IDO1HTR2AHTR2BHTR2C | |
| SCHEMBL21504286 | 0.78 | TAAR1 (0.56) | TAAR1MIFIDO1HTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194764-B1 | PESTICIDAL COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1989-07-12 | — | — | EP | disclosed |
| EP-0194764-A1 | Pesticidal compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1986-09-17 | — | — | EP | disclosed |