Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 5/20 | 0.47 |
| ▸ | NT5E | P21589 | 3/20 | 0.42 |
| ▸ | NSD2 | O96028 | 3/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.42 |
| ▸ | CASP6 | P55212 | 2/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29440243 | 0.98 | MPL (0.49) | MPLNT5ENSD2DUSP3PTPN5 | |
| SCHEMBL4957991 | 0.98 | MPL (0.49) | MPLNT5ENSD2DUSP3PTPN5 | |
| SCHEMBL31344266 | 0.96 | MPL (0.47) | MPLNT5ENSD2DUSP3PTPN5 | |
| SCHEMBL15523070 | 0.96 | MPL (0.47) | MPLNT5ENSD2DUSP3PTPN5 | |
| SCHEMBL217202 | 0.96 | MPL (0.47) | MPLNT5ENSD2DUSP3PTPN5 | |
| SCHEMBL2776938 | 0.96 | MPL (0.47) | MPLNT5ENSD2DUSP3PTPN5 | |
| SCHEMBL590946 | 0.96 | MPL (0.47) | MPLNT5ENSD2DUSP3PTPN5 | |
| SCHEMBL29431679 | 0.94 | MPL (0.49) | MPLNT5ENSD2DUSP3PTPN5 | |
| SCHEMBL112192 | 0.94 | MPL (0.49) | MPLNT5ENSD2DUSP3PTPN5 | |
| SCHEMBL592364 | 0.92 | MPL (0.47) | MPLNT5ENSD2DUSP3PTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4844841-A | Pyrenexulfonic acids useful in fluorescent lipid probes | KOLLER ERNST (AT) | 1989-07-04 | — | — | US | disclosed |