Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 6/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | NT5E | P21589 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4957991 | 1.00 | MPL (0.49) | MPLAURKAAURKBCYP1A2NT5E | |
| SCHEMBL10595679 | 0.98 | MPL (0.47) | MPLAURKAAURKBCYP1A2NT5E | |
| SCHEMBL15523070 | 0.98 | MPL (0.47) | MPLAURKAAURKBCYP1A2NT5E | |
| SCHEMBL590946 | 0.98 | MPL (0.47) | MPLAURKAAURKBCYP1A2NT5E | |
| SCHEMBL112192 | 0.96 | MPL (0.49) | MPLAURKAAURKBCYP1A2NT5E | |
| SCHEMBL29431679 | 0.96 | MPL (0.49) | MPLAURKAAURKBCYP1A2NT5E | |
| SCHEMBL217202 | 0.94 | MPL (0.47) | MPLAURKAAURKBCYP1A2NT5E | |
| SCHEMBL592364 | 0.94 | MPL (0.47) | MPLAURKAAURKBCYP1A2NT5E | |
| SCHEMBL2776938 | 0.94 | MPL (0.47) | MPLAURKAAURKBCYP1A2NT5E | |
| SCHEMBL31344266 | 0.94 | MPL (0.47) | MPLAURKAAURKBCYP1A2NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230358677-A1 | Reversible Excited-State Photoacids and Photobases as Dynamic Fluorescence Sensors of Protonic Species | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2023-11-09 | — | — | US | claimed |
| CN-114646620-A | Optical sensor element, optical pH sensor and method for monitoring the function of an optical pH sensor | 恩德莱斯和豪瑟尔分析仪表两合公司 | 2022-06-21 | — | — | CN | claimed |
| EP-3997462-A1 | ASSAYS FOR IMPROVING AUTOMATED ANTIMICROBIAL SUSCEPTIBILITY TESTING ACCURACY | Selux Diagnostics Inc. (US) | 2022-05-18 | — | — | EP | claimed |
| WO-2025123135-A1 | ASSAY FOR DETECTION AND QUANTIFICATION OF PFAS COMPOUNDS | FREDSENSE TECHNOLOGIES CORP. (CA) | 2025-06-19 | — | — | WO | disclosed |
| WO-2025121223-A1 | AROMATIC POLYSULFONE | 住友化学株式会社 | 2025-06-12 | — | — | WO | disclosed |
| CN-119899909-A | Method for detecting fungi in turf grass by LAMP assay with novel primer group | 先正达参股股份有限公司 | 2025-04-29 | — | — | CN | disclosed |
| US-12226494-B2 | Pharmaceutical compositions comprising Gd-complexes and polyarylene additives | BRACCO IMAGING S.P.A. (IT) | 2025-02-18 | — | — | US | disclosed |
| CN-111684081-B | Method for detecting fungi in turf grass by LAMP assay with novel primer group | 先正达参股股份有限公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-117730159-A | Diagnostic method for biological sample, diagnostic kit for biological sample and oligonucleotide | 奥斯瓦道·克鲁兹基金会 | 2024-03-19 | — | — | CN | disclosed |
| CN-117447653-A | Cationic cyclodextrin microsphere and preparation method and application thereof | 科睿驰（深圳）医疗科技发展有限公司 | 2024-01-26 | — | — | CN | disclosed |
| US-20230358677-A1 | Reversible Excited-State Photoacids and Photobases as Dynamic Fluorescence Sensors of Protonic Species | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2023-11-09 | — | — | US | disclosed |
| CN-116710755-A | LAMP assay devices and methods using RNA/DNA isothermal amplification for pathogen identification | 奥斯瓦道·克鲁兹基金会 | 2023-09-05 | — | — | CN | disclosed |
| EP-4077707-A1 | A REAL-TIME, ADD-AND-READ FLUORESCENCE-BASED ASSAY FOR TESTING FUNCTION AND DRUG INTERACTIONS OF OATP TRANSPORTERS | Cellpharma Kft. (HU) | 2022-10-26 | — | — | EP | disclosed |
| CN-114646620-A | Optical sensor element, optical pH sensor and method for monitoring the function of an optical pH sensor | 恩德莱斯和豪瑟尔分析仪表两合公司 | 2022-06-21 | — | — | CN | disclosed |
| EP-3997462-A1 | ASSAYS FOR IMPROVING AUTOMATED ANTIMICROBIAL SUSCEPTIBILITY TESTING ACCURACY | Selux Diagnostics Inc. (US) | 2022-05-18 | — | — | EP | disclosed |
| US-20220062444-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING GD-COMPLEXES AND POLYARYLENE ADDITIVES | BRACCO IMAGING S.P.A. (IT) | 2022-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12226494-B2 | Pharmaceutical compositions comprising Gd-complexes and polyarylene additives | GRN, GALC, ABCB11 | MPL 1746/4885AURKA 2587/4885AURKB 2542/4885 |
| US-20220062444-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING GD-COMPLEXES AND POLYARYLENE ADDITIVES | GRN, GALC, ABCB11 | MPL 1746/4885AURKA 2587/4885AURKB 2542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.