SCHEMBL10596083

SCHEMBL10596083

CCCCONc1ccc(N(CC)CC)cc1C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 12/20 0.45
LMNA P02545 6/20 0.45
HTT P42858 4/20 0.45
S100B P04271 1/20 0.45
GFER P55789 5/20 0.44
MAPK1 P28482 4/20 0.44
ALDH1A1 P00352 3/20 0.44
NPSR1 Q6W5P4 2/20 0.44
SMN1; SMN2 Q16637 3/20 0.43
HSD17B10 Q99714 2/20 0.43
ALOX15 P16050 2/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
RPS6KA2 Q15349 1/20 0.43
CYP2C19 P33261 2/20 0.42
CYP1A2 P05177 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
POLB P06746 4/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10435127 0.84 S100B (0.50) MAPTLMNAHTTS100BGFER
SCHEMBL5437784 0.80 MAPT (0.53) MAPTLMNAHTTS100BGFER
SCHEMBL9191525 0.78 MAPT (0.44) MAPTLMNAHTTS100BGFER
SCHEMBL8594962 0.77 RPS6KA2 (0.52) MAPTLMNAHTTS100BGFER
SCHEMBL28235239 0.73 HTT (0.44) MAPTLMNAHTTSMN1; SMN2NPC1
SCHEMBL4636720 0.73 S100B (0.59) MAPTLMNAHTTS100BGFER
SCHEMBL7770385 0.73 S100B (0.55) MAPTLMNAHTTS100BGFER
SCHEMBL3914779 0.73 S100B (0.55) MAPTLMNAHTTS100BGFER
SCHEMBL2112282 0.72 MAPT (0.36) MAPTLMNAHTTS100BGFER
SCHEMBL9258297 0.72 MAPT (0.43) MAPTLMNAHTTS100BGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4822726-A HIGH SILVER CHLORIDE CONCENTRATION FUJI PHOTO FILM CO., LTD. (JP) 1989-04-18 US disclosed