Sugi Predict

Sugi Predict / Targets / S100B

S100B

Protein S100-B · P04271 · S100B on Sugi Atlas →

8,764 patent compounds predicted against S100B, 5,643 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
4-(Benzylideneamino)Phenol 4-(Benzylideneamino)Phenol (SCHEMBL1877533) 0.71 3/20
4-(Benzylideneamino)Phenol 4-(Benzylideneamino)Phenol (SCHEMBL1877535) 0.71 3/20
SCHEMBL2311078 SCHEMBL2311078 0.71 3/20
SCHEMBL2311083 SCHEMBL2311083 0.71 3/20
SCHEMBL1033697 SCHEMBL1033697 0.61 3/20
SCHEMBL1033699 SCHEMBL1033699 0.61 3/20
SCHEMBL333458 SCHEMBL333458 0.59 3/20
SCHEMBL333459 SCHEMBL333459 0.59 3/20
SCHEMBL1603197 SCHEMBL1603197 0.51 3/20
SCHEMBL358190 SCHEMBL358190 0.65 2/20
SCHEMBL358396 SCHEMBL358396 0.65 2/20
SCHEMBL1110600 SCHEMBL1110600 0.65 2/20
SCHEMBL1127082 SCHEMBL1127082 0.65 2/20
SCHEMBL1339840 SCHEMBL1339840 0.65 2/20
SCHEMBL1136241 SCHEMBL1136241 0.61 2/20
SCHEMBL1339913 SCHEMBL1339913 0.61 2/20
SCHEMBL358763 SCHEMBL358763 0.59 2/20
SCHEMBL997022 SCHEMBL997022 0.59 2/20
SCHEMBL1110503 SCHEMBL1110503 0.59 2/20
SCHEMBL1110535 SCHEMBL1110535 0.59 2/20

Clinical trials — most relevant to S100B by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Comparison of Neuroprotection by Propofol and Desflurane for POCD Following Subarachnoid Hemorrhage Surgery PHASE4COMPLETED
Dexmedetomidine and Magnesium Sulfate in the Reduction Cognitive Dysfunction in Geriatrics PHASE1RECRUITING
Influence of Morphine or Ketamine or Saline Applied During In-hospital Cardiopulmonary Resuscitation on Early Survival PHASE1UNKNOWN
Neurological Prognostication of Patients in Therapeutic Hypothermia After Cardiac Arrest nanCOMPLETED
Diagnostic Performance of the S100B Protein in the Prognosis of Patients With Mild Head Trauma With Risk of Complications in Patients Over 65 Years Old. nanUNKNOWN
S100 Protein in Minor/Mild Traumatic Brain Injury nanCOMPLETED
Relationship of Gestational Age and Urine Concentration of S100B in Preterm and Term Infants in the First Week of Life nanCOMPLETED
Single-center Transversal Observational Study on the Evaluation of S100B Changes in Subjects Attending the Emergency Department With Head Trauma nanRECRUITING
Neural Damage and Anesthetic Treatment in the Preeclamptic Parturient; a Prospective Observational Study. nanUNKNOWN
Evaluation of s100β, NSE and GFAP Levels in Renal Transplantation nanCOMPLETED
S100B in the Care of Non-traumatic Headaches in the Emergency Department nanCOMPLETED
S100β and Neuron Specific Enolase Levels in Liver Transplantation nanCOMPLETED
Study Assessing Evaluation of the Interest of Serum S100B Protein Determination in the Management of Pediatric Mild Traumatic Brain Injury nanCOMPLETED
Urine Concentration of S100B in Extremely Premature Infants nanCOMPLETED
Diagnosis of Sport-related Concussion Using Urine Metabolites nanCOMPLETED
Serum S100B Protein Assay in Mild Head Injury nanUNKNOWN
PRecisiOn Medicine In StrokE: Evolution of Plasma Brain-Derived Tau in Acute Stroke nanRECRUITING
Evaluation of the Predictive Impact of Serum S100B and S100B Polymorphisms on Postoperative Cognitive Dysfunction and Delirium nanCOMPLETED
Protein S100B Versus Neutrophils/Lymphocytes Ratio in Early Prediction of Brain Injury nanCOMPLETED
Predicting Postoperative Delirium Using EEG, Genetics and Neurobiomarkers of Cerebral Injury nanCOMPLETED
Role of Concentration of Biomarkers S100B and NSE in Serum in Mild and Moderate Head Trauma nanUNKNOWN
Evaluation of the Role of Neurodegeneration in Schizophrenia nanCOMPLETED
Interest of the S100B Protein Assay in Mild Traumatic Brain Injuries at the DOUAI Hospital nanCOMPLETED
Using the S100B Protein for Emergency Headache Management Care (S100) nanCOMPLETED
Protein S100 Beta as a Predictor of Resuscitation Outcome nanUNKNOWN
Usefulness of Biomarkers in the Management of Mild Traumatic Brain Injury in Adults (Biotraumap) nanCOMPLETED
Clinicolaboratory Predictors of Outcome in Children With Encephalitis nanNOT_YET_RECRUITING
Ethnic Specificities of S100B Protein Blood Level in Guadeloupe: Cross-sectional Study in Healthy Subjects nanRECRUITING
Using Routine Inflammatory and Metabolic Blood Tests (Bedside Included) to Predict Brain Injury in Children After Minor Head Trauma nanNOT_YET_RECRUITING
Neuronal Damage In Delirium Study nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a S100B binder may also engage these)

ProteinNameSimilarity
Q6YNR6 — 1.000 Q6YNR6 →
P50114 — 1.000 P50114 →
P04631 — 1.000 P04631 →
P02638 — 1.000 P02638 →
P30801 — 0.983 P30801 →
P10462 — 0.982 P10462 →
Q503K9 — 0.979 Q503K9 →
P29034 — 0.979 P29034 →
P05964 — 0.976 P05964 →
Q2EN75 — 0.975 Q2EN75 →
P14069 — 0.975 P14069 →
S100A4 Protein S100-A4 0.972 landscape →
P05942 — 0.971 P05942 →
O77691 — 0.971 O77691 →
Q98953 — 0.969 Q98953 →
S100A6 Protein S100-A6 0.968 landscape →
Q7LZT1 — 0.967 Q7LZT1 →
P35467 — 0.967 P35467 →
P07091 — 0.966 P07091 →
P35466 — 0.966 P35466 →
Q9TV56 — 0.965 Q9TV56 →
P24479 — 0.964 P24479 →
P02639 — 0.959 P02639 →
Q8WXG8 — 0.958 Q8WXG8 →
P23297 — 0.957 P23297 →
Q5RC36 — 0.957 Q5RC36 →
S100P Protein S100-P 0.956 landscape →
P56565 — 0.956 P56565 →
P97352 — 0.956 P97352 →
Q96FQ6 — 0.951 Q96FQ6 →