Phosphoric Acid

Phosphoric Acid

SCHEMBL10596243

CCCCCCCCCCOc1ccc(C)cc1CCCCCCCCCC.O=P(O)(O)O

nearest known ligand 0.53

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.53
ALDH1A1 P00352 3/20 0.53
NPSR1 Q6W5P4 2/20 0.53
THRB P10828 2/20 0.53
GAA P10253 1/20 0.53
HTT P42858 3/20 0.51
MAPK1 P28482 3/20 0.51
RAD52 P43351 2/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
APAF1 O14727 2/20 0.47
POLB P06746 2/20 0.47
KDM4E B2RXH2 1/20 0.47
LMNA P02545 1/20 0.47
BLM P54132 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
S1PR2 O95136 2/20 0.46
S1PR1 P21453 2/20 0.46
S1PR3 Q99500 2/20 0.46
LPAR2 Q9HBW0 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL9818193 1.00 MAPT (0.53) MAPTALDH1A1NPSR1THRBGAA
Phosphoric Acid SCHEMBL11323353 1.00 MAPT (0.53) MAPTALDH1A1NPSR1THRBGAA
Phosphoric Acid SCHEMBL10622150 0.92 MAPT (0.49) MAPTALDH1A1NPSR1THRBGAA
SCHEMBL11215013 0.91 MAPT (0.61) MAPTALDH1A1NPSR1THRBGAA
SCHEMBL15033259 0.86 MAPT (0.52) MAPTALDH1A1NPSR1THRBGAA
SCHEMBL11283038 0.84 GAA (0.41) MAPTALDH1A1NPSR1THRBGAA
SCHEMBL11619328 0.84 GAA (0.41) MAPTALDH1A1NPSR1THRBGAA
SCHEMBL3683527 0.84 GAA (0.41) MAPTALDH1A1NPSR1THRBGAA
Phosphoric Acid SCHEMBL4712516 0.82 CETP (0.48) PTGER1PTGER4PTGER3PTGER2
Phosphoric Acid SCHEMBL4711876 0.82 CETP (0.48) PTGER1PTGER4PTGER3PTGER2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0138599-B1 POLYPHENYLENE ETHER RESIN COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1989-03-29 EP disclosed
WO-1987007901-A1 FLAME RETARDANT POLYPHENYLENE ETHER-POLYSTYRENE BLENDS OF INCREASED HEAT RESISTANCE AND METHOD OF ACHIEVEMENT GENERAL ELECTRIC COMPANY (US) 1987-12-30 WO disclosed
US-4624979-A STYRENE-BROMINATED STYRENE COPOLYMER GENERAL ELECTRIC COMPANY (US) 1986-11-25 US disclosed
EP-0065009-B1 CLAY FILLED POLYPHENYLENE ETHER COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 1986-02-26 EP disclosed
US-4556685-A BLENDS, IMPACT STRENGTH, MOLDABLE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1985-12-03 US disclosed
EP-0151261-A1 Polyphenylene ether resin blends reinforced with finely divided particulate clay of narrow size distribution GENERAL ELECTRIC COMPANY (US) 1985-08-14 EP disclosed
US-4525508-A STIFFNESS, DUCTILITY GENERAL ELECTRIC COMPANY (US) 1985-06-25 US disclosed
EP-0138599-A2 Polyphenylene ether resin composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1985-04-24 EP disclosed
US-4478970-A PLASTICIZING GENERAL ELECTRIC COMPANY (US) 1984-10-23 US disclosed
EP-0065009-A4 CLAY FILLED POLYPHENYLENE ETHER COMPOSITIONS. GEN ELECTRIC (US) 1983-03-17 EP disclosed
US-4317761-A MOLDING MATERIAL WITH HIGH IMPACT STRENGTH GENERAL ELECTRIC COMPANY (US) 1982-03-02 US disclosed
EP-0016045-A1 COMPOSITIONS COMPRISING POLYPHENYLENE ETHER AND POLY(VINYL CHLORIDE) RESINS GENERAL ELECTRIC COMPANY (US) 1980-10-01 EP disclosed
EP-0016045-A4 COMPOSITIONS COMPRISING POLYPHENYLENE ETHER AND POLY(VINYL CHLORIDE) RESINS. GEN ELECTRIC (US) 1980-09-29 EP disclosed
WO-1980000028-A1 COMPOSITIONS COMPRISING POLYPHENYLENE ETHER AND POLY(VINYL CHLORIDE)RESINS GEN ELECTRIC (US) 1980-01-10 WO disclosed
US-4154712-A VINYLAROMATIC-CONJUGATED DIENE BLOCK POLYMER GENERAL ELECTRIC COMPANY (US) 1979-05-15 US disclosed
US-4147739-A Thermoplastic molding compositions of rubber modified copolymers of a vinyl aromatic compound and an α,β-unsaturated cyclic anhydride GENERAL ELECTRIC COMPANY (US) 1979-04-03 US disclosed
US-4145377-A MOLDING MATERIALS GENERAL ELECTRIC COMPANY (US) 1979-03-20 US disclosed
US-4123410-A POLY(1,4-BUTYLENE TEREPHTHALATE, PLASTICIZER GENERAL ELECTRIC COMPANY (US) 1978-10-31 US disclosed
US-4113797-A BLOCK POLYMERS GENERAL ELECTRIC COMPANY (US) 1978-09-12 US disclosed
US-4077934-A Method of preparing compositions that comprise a polyphenylene ether resin and an alkenyl aromatic resin GENERAL ELECTRIC COMPANY (US) 1978-03-07 US disclosed