Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MGAM | O43451 | 1/20 | 0.54 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.54 |
| ▸ | SI | P14410 | 1/20 | 0.54 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10617898 | 0.89 | GAA (0.58) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL10617911 | 0.83 | GAA (0.55) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL10617271 | 0.79 | CDK2 (0.41) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL10620347 | 0.76 | TSHR (0.44) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL10617443 | 0.76 | GAA (0.60) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL10617892 | 0.75 | GAA (0.58) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL10617365 | 0.75 | GAA (0.58) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL10617187 | 0.74 | GAA (0.78) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL9688992 | 0.74 | GAA (0.54) | GAATSHRALDH1A1KDM4EHSD17B10 | |
| SCHEMBL10617902 | 0.73 | TSHR (0.54) | GAAMGAMAMY1ASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1207267-A | — | — | None | — | — | JP | disclosed |
| JP-H01207267-A | PYRIDINE DERIVATIVE AND REMEDY CONTAINING SAID COMPOUND FOR HEPATOPATHY | YAMANOUCHI PHARMACEUT CO LTD | 1989-08-21 | — | — | JP | disclosed |