Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | BAP1 | Q92560 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10367692 | 0.94 | NR1I2 (0.56) | GAASMN1; SMN2NPC1TSHRATM | |
| SCHEMBL9806975 | 0.87 | MAPT (0.56) | GAASMN1; SMN2NPC1TSHRALDH1A1 | |
| SCHEMBL7414856 | 0.81 | NR1I2 (0.67) | GAASMN1; SMN2TSHRALDH1A1HSD17B10 | |
| SCHEMBL7025790 | 0.78 | NR1I2 (0.56) | GAASMN1; SMN2NPC1TSHRALDH1A1 | |
| SCHEMBL10675417 | 0.75 | NR1I2 (0.53) | GAASMN1; SMN2TSHRALDH1A1HSD17B10 | |
| SCHEMBL7106117 | 0.75 | KDM4E (0.56) | GAASMN1; SMN2TSHRALDH1A1HSD17B10 | |
| SCHEMBL9690101 | 0.75 | KMT2A (0.43) | GAATSHRATMALDH1A1HSD17B10 | |
| SCHEMBL10596292 | 0.74 | GAA (0.54) | GAASMN1; SMN2NPC1TSHRALDH1A1 | |
| SCHEMBL3034560 | 0.74 | NR1I2 (0.73) | GAASMN1; SMN2TSHRALDH1A1HSD17B10 | |
| SCHEMBL29676206 | 0.74 | NR1I2 (0.73) | GAASMN1; SMN2TSHRALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0158211-B1 | 1,4-DIHYDROPYRIDIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USES AS MEDICAMENTS | LABORATORIOS DELAGRANGE S.A. (ES) | 1992-08-26 | — | — | EP | disclosed |
| US-4722931-A | MUSCLE RELAXANTS | LABORATORIOS DELAGRANGE (ES) | 1988-02-02 | — | — | US | disclosed |
| EP-0158211-A2 | 1,4-Dihydropyridin derivatives, process for their preparation and their uses as medicaments | LABORATORIOS DELAGRANGE S.A. (ES) | 1985-10-16 | — | — | EP | disclosed |