Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 2/20 | 0.37 |
| ▸ | LDHB | P07195 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24040210 | 0.86 | PDE10A (0.37) | NOTUMLDHALDHBCYP3A4ACHE | |
| SCHEMBL27655427 | 0.83 | TDP1 (0.39) | METAP2MCL1NOTUMLDHALDHB | |
| SCHEMBL1257806 | 0.81 | METAP2 (0.45) | METAP2MCL1NOTUMLDHALDHB | |
| SCHEMBL31643852 | 0.81 | METAP2 (0.45) | METAP2MCL1NOTUMLDHALDHB | |
| SCHEMBL27289184 | 0.81 | CYP1A2 (0.41) | NOTUMCYP1A2ALDH1A1AKR1C3KMT2A | |
| SCHEMBL6907853 | 0.79 | METAP2 (0.44) | METAP2MCL1NOTUMLDHALDHB | |
| SCHEMBL6916711 | 0.79 | METAP2 (0.44) | METAP2MCL1NOTUMLDHALDHB | |
| SCHEMBL6913510 | 0.79 | METAP2 (0.44) | METAP2MCL1NOTUMLDHALDHB | |
| SCHEMBL6914942 | 0.79 | METAP2 (0.44) | METAP2MCL1NOTUMLDHALDHB | |
| SCHEMBL6912987 | 0.79 | METAP2 (0.44) | METAP2MCL1NOTUMLDHALDHB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0181526-B1 | BENZOIC ACID DERIVATIVES | Chugai Seiyaku Kabushiki Kaisha (JP) | 1989-01-18 | — | — | EP | disclosed |
| US-4698364-A | INFECTION CONTROL | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1987-10-06 | — | — | US | disclosed |
| EP-0181526-A1 | Benzoic acid derivatives | Chugai Seiyaku Kabushiki Kaisha (JP) | 1986-05-21 | — | — | EP | disclosed |