Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10454012 | 0.89 | TSHR (0.49) | TSHRSMN1; SMN2PKMALDH1A1GAA | |
| SCHEMBL6997281 | 0.87 | TSHR (0.53) | TSHRSMN1; SMN2PKMALDH1A1GAA | |
| SCHEMBL5495599 | 0.80 | TDP1 (0.52) | TSHRSMN1; SMN2PKMALDH1A1GAA | |
| SCHEMBL21768538 | 0.79 | TSHR (0.53) | TSHRSMN1; SMN2PKMALDH1A1GAA | |
| SCHEMBL6998791 | 0.79 | TSHR (0.46) | TSHRSMN1; SMN2PKMALDH1A1GAA | |
| SCHEMBL10595554 | 0.77 | — | — | |
| SCHEMBL11500201 | 0.76 | TSHR (0.47) | TSHRSMN1; SMN2PKMALDH1A1GAA | |
| SCHEMBL56403 | 0.76 | TSHR (0.63) | TSHRSMN1; SMN2PKMALDH1A1GAA | |
| SCHEMBL9719094 | 0.75 | TSHR (0.53) | TSHRSMN1; SMN2PKMALDH1A1GAA | |
| SCHEMBL2053300 | 0.74 | TSHR (0.50) | TSHRSMN1; SMN2PKMALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0104403-B1 | NEW METHOD FOR THE SYNTHESIS OF 5-THIO-1,2,3-THIADIAZOLE | AMERICAN CYANAMID COMPANY (US) | 1989-01-25 | — | — | EP | claimed |
| EP-0104403-B1 | NEW METHOD FOR THE SYNTHESIS OF 5-THIO-1,2,3-THIADIAZOLE | AMERICAN CYANAMID COMPANY (US) | 1989-01-25 | — | — | EP | disclosed |
| US-4454336-A | Derivatives of 3-(formylmethylthio)-propanoate | AMERICAN CYANAMID COMPANY (US) | 1984-06-12 | — | — | US | disclosed |
| EP-0104403-A1 | New method for the synthesis of 5-thio-1,2,3-thiadiazole | AMERICAN CYANAMID COMPANY (US) | 1984-04-04 | — | — | EP | disclosed |