Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 3/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21768538 | 0.94 | TSHR (0.53) | TSHRPKMSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL5495599 | 0.91 | TDP1 (0.52) | TSHRPKMSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL11500201 | 0.87 | TSHR (0.47) | TSHRPKMSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL90430 | 0.84 | TSHR (0.55) | TSHRPKMSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL31122207 | 0.82 | TSHR (0.59) | TSHRPKMSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL19899858 | 0.82 | TSHR (0.47) | TSHRPKMSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL19899967 | 0.82 | TSHR (0.47) | TSHRPKMSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL6997281 | 0.82 | TSHR (0.53) | TSHRPKMSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL18921054 | 0.82 | TSHR (0.53) | TSHRPKMSMN1; SMN2ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL10749496 | 0.82 | TSHR (0.53) | TSHRPKMSMN1; SMN2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120330061-A1 | PREPARATION METHOD OF N,N'-DIALKYL-3,3'-DITHIODIPROPIONAMIDE | SK CHEMICALS CO., LTD. (KR) | 2012-12-27 | — | — | US | disclosed |
| CN-102791685-A | Method for preparing N,N'-dialkyl-3,3'-dithiodipropionamides | SK CHEMICALS CO LTD | 2012-11-21 | — | — | CN | disclosed |
| WO-2011074815-A3 | METHOD FOR PREPARING N,N'-DIALKYL-3,3'-DITHIODIPROPIONAMIDES | 에스케이케미칼주식회사 (KR) | 2011-11-03 | — | — | WO | disclosed |
| WO-2011074815-A2 | METHOD FOR PREPARING N,N'-DIALKYL-3,3'-DITHIODIPROPIONAMIDES | 에스케이케미칼주식회사 (KR) | 2011-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120330061-A1 | PREPARATION METHOD OF N,N'-DIALKYL-3,3'-DITHIODIPROPIONAMIDE | NAPEPLD, NAAA, NISCH | TSHR 1780/4885PKM 2760/4885SMN1; SMN2 3357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.