Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.83 |
| ▸ | HIF1A | Q16665 | 13/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.70 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.70 |
| ▸ | PGR | P06401 | 5/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.70 |
| ▸ | SERPINA6 | P08185 | 4/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | SHBG | P04278 | 2/20 | 0.70 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.70 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.65 |
| ▸ | AR | P10275 | 3/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10598493 | 1.00 | KMT2A (0.83) | KMT2AHIF1AHSD17B10CYP3A4NR3C1 | |
| SCHEMBL142384 | 0.91 | KMT2A (1.00) | KMT2AHIF1AHSD17B10CYP3A4NR3C1 | |
| SCHEMBL142385 | 0.91 | KMT2A (1.00) | KMT2AHIF1AHSD17B10CYP3A4NR3C1 | |
| SCHEMBL142686 | 0.91 | KMT2A (1.00) | KMT2AHIF1AHSD17B10CYP3A4NR3C1 | |
| SCHEMBL137530 | 0.90 | KMT2A (0.84) | KMT2AHIF1AHSD17B10CYP3A4NR3C1 | |
| SCHEMBL17714999 | 0.90 | KMT2A (0.84) | KMT2AHIF1AHSD17B10CYP3A4NR3C1 | |
| SCHEMBL17726095 | 0.90 | KMT2A (0.84) | KMT2AHIF1AHSD17B10CYP3A4NR3C1 | |
| SCHEMBL137529 | 0.90 | KMT2A (0.84) | KMT2AHIF1AHSD17B10CYP3A4NR3C1 | |
| SCHEMBL10393880 | 0.90 | KMT2A (0.84) | KMT2AHIF1AHSD17B10CYP3A4NR3C1 | |
| SCHEMBL13150977 | 0.90 | KMT2A (0.84) | KMT2AHIF1AHSD17B10CYP3A4NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119278054-A | Glycosylated prodrugs | 莱顿大学 | 2025-01-07 | — | — | CN | claimed |
| US-20230332237-A1 | Molecular Biomarkers for Predicting Patient Response to Steroid Therapy | NATIONAL INSTITUTES OF HEALTH | 2023-10-19 | — | — | US | claimed |
| EP-0186948-B1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF 17ALPHA-HYDROXYPROGESTERONES AND CORTICOIDS FROM AN ENOL STEROID | THE UPJOHN COMPANY (US) | 1989-01-25 | — | — | EP | claimed |
| EP-0186948-A1 | Process and intermediates for the preparation of 17alpha-hydroxyprogesterones and corticoids from an enol steroid | THE UPJOHN COMPANY (US) | 1986-07-09 | — | — | EP | claimed |
| US-20230332237-A1 | Molecular Biomarkers for Predicting Patient Response to Steroid Therapy | NATIONAL INSTITUTES OF HEALTH | 2023-10-19 | — | — | US | disclosed |
| WO-2010121814-A1 | PHARMACEUTICAL COMPOSITION, COMPRISING A STEROID-DEHYDROGENASE-REDUCTASE INHIBITOR, AND A MINERALOCORTICOID RECEPTOR ANTAGONIST | ONTOCHEM GMBH (DE) | 2010-10-28 | — | — | WO | disclosed |
| EP-0186948-B1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF 17ALPHA-HYDROXYPROGESTERONES AND CORTICOIDS FROM AN ENOL STEROID | THE UPJOHN COMPANY (US) | 1989-01-25 | — | — | EP | disclosed |
| US-4613463-A | Process and intermediates for the preparation of 17 alphahydroxyprogesterones and corticoids from an enol steroid | THE UPJOHN COMPANY (US) | 1986-09-23 | — | — | US | disclosed |
| EP-0042451-B1 | PROCESS FOR THE PREPARATION OF 11-BETA-HYDROXY STEROIDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1983-06-22 | — | — | EP | disclosed |
| US-4353985-A | FERMENTATION WITH CURVULARIA | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-10-12 | — | — | US | disclosed |