Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.84 |
| ▸ | HIF1A | Q16665 | 11/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.81 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.81 |
| ▸ | TSHR | P16473 | 2/20 | 0.81 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.72 |
| ▸ | PGR | P06401 | 5/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.72 |
| ▸ | SERPINA6 | P08185 | 4/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.72 |
| ▸ | MAPT | P10636 | 2/20 | 0.72 |
| ▸ | SHBG | P04278 | 2/20 | 0.72 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.72 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.72 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.68 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.68 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.68 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL137529 | 1.00 | KMT2A (0.84) | KMT2AHIF1ACYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL6851992 | 1.00 | KMT2A (0.84) | KMT2AHIF1ACYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL13152832 | 1.00 | KMT2A (0.84) | KMT2AHIF1ACYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL9458663 | 1.00 | KMT2A (0.84) | KMT2AHIF1ACYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL10393880 | 1.00 | KMT2A (0.84) | KMT2AHIF1ACYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL13150977 | 1.00 | KMT2A (0.84) | KMT2AHIF1ACYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL17714999 | 1.00 | KMT2A (0.84) | KMT2AHIF1ACYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL17726095 | 1.00 | KMT2A (0.84) | KMT2AHIF1ACYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL11702370 | 0.93 | HIF1A (0.81) | KMT2AHIF1ACYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL142385 | 0.91 | KMT2A (1.00) | KMT2AHIF1ACYP3A4HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058979-A1 | METHODS AND REAGENTS FOR THE TREATMENT OF IMMUNOINFLAMMATORY DISORDERS | ZALICUS INC. (US) | 2012-03-08 | — | — | US | claimed |
| US-8080553-B2 | Methods and reagents for the treatment of immunoinflammatory disorders | ZALICUS INC. (US) | 2011-12-20 | — | — | US | claimed |
| US-20070010502-A1 | Methods and reagents for the treatment of immunoinflammatory disorders | COMBINATORX INC. (US) | 2007-01-11 | — | — | US | claimed |
| EP-0350488-B1 | 1,2-DEHYDROGENATION OF STEROIDAL 21-ESTERS WITH A. SIMPLEX | THE UPJOHN COMPANY (US) | 1993-09-08 | — | — | EP | claimed |
| EP-0374185-B1 | IMPROVED 9$g(a)-DEHALOGENATION PROCESS | THE UPJOHN COMPANY (US) | 1993-02-10 | — | — | EP | claimed |
| EP-0374185-A1 | IMPROVED 9-g(a)-DEHALOGENATION PROCESS. | UPJOHN CO (US) | 1990-06-27 | — | — | EP | claimed |
| WO-1989001482-A1 | IMPROVED 9alpha-DEHALOGENATION PROCESS | THE UPJOHN COMPANY (US) | 1989-02-23 | — | — | WO | claimed |
| EP-0186948-B1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF 17ALPHA-HYDROXYPROGESTERONES AND CORTICOIDS FROM AN ENOL STEROID | THE UPJOHN COMPANY (US) | 1989-01-25 | — | — | EP | claimed |
| EP-0186948-A1 | Process and intermediates for the preparation of 17alpha-hydroxyprogesterones and corticoids from an enol steroid | THE UPJOHN COMPANY (US) | 1986-07-09 | — | — | EP | claimed |
| US-20250099457-A1 | HETEROARYL-KETONE FUSED AZADECALIN GLUCOCORTICOID RECEPTOR MODULATORS | CORCEPT THERAPEUTICS, INC. (US) | 2025-03-27 | — | — | US | disclosed |
| EP-4434584-A2 | HETEROARYL-KETONE FUSED AZADECALIN GLUCOCORTICOID RECEPTOR MODULATORS | Corcept Therapeutics Incorporated (US) | 2024-09-25 | — | — | EP | disclosed |
| EP-4119561-B1 | HETEROARYL-KETONE FUSED AZADECALIN GLUCOCORTICOID RECEPTOR MODULATORS | CORCEPT THERAPEUTICS INC (US) | 2024-09-11 | — | — | EP | disclosed |
| US-20230330084-A1 | HETEROARYL-KETONE FUSED AZADECALIN GLUCOCORTICOID RECEPTOR MODULATORS | CORCEPT THERAPEUTICS, INC. (US) | 2023-10-19 | — | — | US | disclosed |
| US-11576907-B2 | Heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators | CORCEPT THERAPEUTICS, INC. (US) | 2023-02-14 | — | — | US | disclosed |
| EP-0042451-B1 | PROCESS FOR THE PREPARATION OF 11-BETA-HYDROXY STEROIDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1983-06-22 | — | — | EP | disclosed |
| US-4353985-A | FERMENTATION WITH CURVULARIA | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-10-12 | — | — | US | disclosed |
| EP-0054810-A2 | Process for the preparation of 3-oxo-delta-1,4-steroids | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-06-30 | — | — | EP | disclosed |
| EP-0042451-A1 | Process for the preparation of 11-beta-hydroxy steroids | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-12-30 | — | — | EP | disclosed |
| US-4224320-A | Novel steroids of the pregnane series, substituted in the 17-position, their manufacture and their use | SCHERING, AKTIENGESELLSCHAFT (DE) | 1980-09-23 | — | — | US | disclosed |
| US-4207316-A | ANTIINFLAMMATORY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1980-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010502-A1 | Methods and reagents for the treatment of immunoinflammatory disorders | IL5, TPMT, TSLP | KMT2A 3089/4885HIF1A 1602/4885CYP3A4 1322/4885 |
| US-20250099457-A1 | HETEROARYL-KETONE FUSED AZADECALIN GLUCOCORTICOID RECEPTOR MODULATORS | NR3C1, GRIN3A, NR3C2 | KMT2A 1504/4885HIF1A 4622/4885CYP3A4 1984/4885 |
| US-11576907-B2 | Heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators | NR3C1, NR3C2, NR5A1 | KMT2A 1550/4885HIF1A 4646/4885CYP3A4 374/4885 |
| US-20120058979-A1 | METHODS AND REAGENTS FOR THE TREATMENT OF IMMUNOINFLAMMATORY DISORDERS | IL5, TPMT, TSLP | KMT2A 3089/4885HIF1A 1602/4885CYP3A4 1322/4885 |
| US-20230330084-A1 | HETEROARYL-KETONE FUSED AZADECALIN GLUCOCORTICOID RECEPTOR MODULATORS | NR3C1, GRIN3A, NR3C2 | KMT2A 1504/4885HIF1A 4622/4885CYP3A4 1984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.