SCHEMBL10598564

SCHEMBL10598564

CC(=O)N[C@@H]1[C@@H](OC(C)CN(C(=O)[C@H](C)N)[C@H](CCC(=O)O)C(=O)O)[C@H](O)[C@@H](CO)O[C@@H]1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.57
NOD2 Q9HC29 1/20 0.54
ALDH1A1 P00352 2/20 0.42
THRB P10828 1/20 0.42
SELP P16109 5/20 0.41
ESR1 P03372 2/20 0.40
PGR P06401 2/20 0.40
HTR1A P08908 1/20 0.40
ADORA3 P0DMS8 1/20 0.40
AR P10275 1/20 0.40
CHRM1 P11229 1/20 0.40
TBXA2R P21731 1/20 0.40
PTGS1 P23219 1/20 0.40
ADRA1A P35348 1/20 0.40
KCNH2 Q12809 1/20 0.40
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
MMP12 P39900 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alanine SCHEMBL11120060 0.94 NOD2 (0.56) MAPK1NOD2ALDH1A1THRBSELP
SCHEMBL3511875 0.94 MAPK1 (0.56) MAPK1NOD2ALDH1A1THRBSELP
SCHEMBL5270133 0.94 NOD2 (0.57) MAPK1NOD2ALDH1A1THRBSELP
SCHEMBL3229330 0.94 NOD2 (0.57) MAPK1NOD2ALDH1A1THRBSELP
SCHEMBL342953 0.94 NOD2 (0.57) MAPK1NOD2ALDH1A1THRBSELP
Water SCHEMBL769017 0.93 NOD2 (0.57) MAPK1NOD2ALDH1A1THRBSELP
SCHEMBL10723541 0.90 MAPK1 (0.56) MAPK1NOD2ALDH1A1THRBSELP
SCHEMBL11178056 0.89 MAPK1 (0.54) MAPK1NOD2ALDH1A1THRBSELP
SCHEMBL10379368 0.88 MAPK1 (0.54) MAPK1NOD2ALDH1A1THRBSELP
SCHEMBL4452390 0.88 NOD2 (0.55) MAPK1NOD2ALDH1A1THRBSELP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114438003-A Recombinant microorganism having improved ability to produce hydrophobic substance and cell membrane engineering method for production 韩国科学技术院 2022-05-06 CN claimed
CN-107106672-B Monoclonal antibodies against muramyl peptides for the prevention and treatment of immune-mediated diseases 新加坡科技研究局 2021-06-22 CN claimed
US-10316079-B2 Monoclonal antibody against muramyl peptides AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2019-06-11 US claimed
US-20170342136-A1 MONOCLONAL ANTIBODY AGAINST MURAMYL PEPTIDES IN PREVENTION AND TREATMENT OF IMMUNE-MEDIATED DISEASES AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2017-11-30 US claimed
US-9695231-B2 Monoclonal antibody against muramyl peptides AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2017-07-04 US claimed
EP-2909234-A1 MONOCLONAL ANTIBODY AGAINST MURAMYL PEPTIDES Agency For Science, Technology And Research (SG) 2015-08-26 EP claimed
WO-2014070117-A1 MONOCLONAL ANTIBODY AGAINST MURAMYL PEPTIDES AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2014-05-08 WO claimed
EP-0089290-B1 CONJUGATES OF HAPTENES AND MURAMYL PEPTIDES HAVING AN IMMUNOGENIC ACTIVITY, AND COMPOSITIONS CONTAINING THEM ANVAR Agence Nationale de Valorisation de la Recherche (FR) 1989-06-14 EP claimed
US-4698330-A N-ACETYLMURAMYLOLIGOPEPTIDES TO INDUCE A NATURAL SLEEP OF THE SLOW-WAVE TYPE PRESIDENT & FELLOWS OF HARVARD COLLEGE (US) 1987-10-06 US claimed
US-4639512-A Conjugates of haptenes and muramyl-peptides, endowed with immunogenic activity and compositions containing them AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (FR) 1987-01-27 US claimed
US-4548923-A IMMUNOSTIMULANTS, BACTERICIDES, VIRICIDES CIBA GEIGY CORPORATION (US) 1985-10-22 US claimed
US-4370265-A N-ACETYLMURAMYL-L-ALANYL-D-GLUTAMIC ACID AGENCE NATIONALE DE VALORISATION (FR) 1983-01-25 US claimed
US-4357322-A ADMINISTERING MURAMYL OR DESMETHYLMURAMYL DIPEPTIDES SYNTEX (U.S.A.) INC. (US) 1982-11-02 US claimed
US-4186194-A Water soluble agents effective as immunological adjuvants for stimulating, in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (ANVAR) (FR) 1980-01-29 US claimed
US-4172125-A Oil-free adjuvant compositions containing N-acetyl-muramyl-L-alanyl-D-glutamic acid and method of use AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (ANVAR) (FR) 1979-10-23 US claimed
CN-114438003-B Recombinant microorganism having improved ability to produce hydrophobic substance and cell membrane engineering method for preparation thereof 韩国科学技术院 2024-11-19 CN disclosed
CN-114438003-A Recombinant microorganism having improved ability to produce hydrophobic substance and cell membrane engineering method for production 韩国科学技术院 2022-05-06 CN disclosed
US-4172125-A Oil-free adjuvant compositions containing N-acetyl-muramyl-L-alanyl-D-glutamic acid and method of use AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (ANVAR) (FR) 1979-10-23 US disclosed
US-4158052-A Oil-free adjuvant compositions containing N-acetyl-muramyl-L-alanyl-D-isoglutamine AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (ANVAR) (FR) 1979-06-12 US disclosed
US-4153684-A Immunizing and anti-infectious adjuvant agents constituted by N-acetyl-muramyl-L-alanyl-D-glutamic acid derivatives AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (ANVAR) (FR) 1979-05-08 US disclosed