SCHEMBL105986

SCHEMBL105986

O=C(C=NO)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.56
MAPK1 P28482 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
AKT1 P31749 1/20 0.54
NFE2L2 Q16236 1/20 0.52
NPSR1 Q6W5P4 3/20 0.50
CYP1A2 P05177 1/20 0.50
RECQL P46063 2/20 0.48
PLIN1 O60240 2/20 0.48
LMNA P02545 2/20 0.48
MAPT P10636 2/20 0.48
PLIN5 Q00G26 2/20 0.48
ABHD5 Q8WTS1 2/20 0.48
BCHE P06276 1/20 0.48
TNFRSF1A P19438 1/20 0.48
ACHE P22303 1/20 0.48
MAOB P27338 1/20 0.48
CYP1B1 Q16678 1/20 0.48
KMT2A Q03164 2/20 0.47
MEN1 O00255 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1370683 1.00 ALDH1A1 (0.56) ALDH1A1MAPK1TDP1AKT1NFE2L2
Benzene SCHEMBL27436197 1.00 ALDH1A1 (0.56) ALDH1A1MAPK1TDP1AKT1NFE2L2
SCHEMBL2680021 1.00 ALDH1A1 (0.56) ALDH1A1MAPK1TDP1AKT1NFE2L2
SCHEMBL27567550 0.98 ALDH1A1 (0.54) ALDH1A1MAPK1TDP1AKT1NFE2L2
Ammonia Solution, Strong SCHEMBL27875840 0.98 ALDH1A1 (0.54) ALDH1A1MAPK1TDP1AKT1NFE2L2
Hydrochloric Acid SCHEMBL28101398 0.98 ALDH1A1 (0.54) ALDH1A1MAPK1TDP1AKT1NFE2L2
Water SCHEMBL27459091 0.98 ALDH1A1 (0.54) ALDH1A1MAPK1TDP1AKT1NFE2L2
Formaldehyde SCHEMBL27789688 0.96 AKT1 (0.56) ALDH1A1MAPK1TDP1AKT1NFE2L2
Methylamine SCHEMBL28254364 0.94 ALDH1A1 (0.50) ALDH1A1MAPK1TDP1AKT1NFE2L2
Dimethylamine SCHEMBL27602794 0.92 ALDH1A1 (0.54) ALDH1A1MAPK1TDP1AKT1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 652 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110527326-A A kind of aeroge coating and preparation method thereof TANG XUEJIN 2019-12-03 CN claimed
CN-110317177-A The preparation method of pyrimidine salicylic acid oxime ester compound and application as herbicide 常州大学 2019-10-11 CN claimed
CN-110179679-A The biological beauty treatment Face-protecting mask essence of the liquid extract of culture containing umbilical cord mesenchymal stem cells, facial mask and preparation method thereof 贵州医科大学 2019-08-30 CN claimed
CN-110037970-A A kind of hair conditioner with tough anticreep effect 广州科恩生物技术有限公司 2019-07-23 CN claimed
CN-110013530-A A kind of skin repair stoste and preparation method thereof 厦门市中萪研生物科技有限公司 2019-07-16 CN claimed
CN-109893464-A It is a kind of to block the whitening spot-removing skin care item and preparation method thereof for inhibiting reduction melanin 中美杜克(广州)护肤研究中心(普通合伙) 2019-06-18 CN claimed
CN-109897590-A A kind of dual cure reaction type polyurethane hot-melt adhesive and its preparation method and application 美瑞新材料股份有限公司 2019-06-18 CN claimed
CN-109613744-A A kind of quantum dot display panel, quantum stippling film wait for the preparation method of hydrojet 深圳市华星光电技术有限公司 2019-04-12 CN claimed
CN-109593169-A A method of Tobacco Seed Germination bed is prepared using offal 河南农业大学 2019-04-09 CN claimed
CN-106414398-B Compound, active energy ray-curable composition, cured product thereof, printing ink, and ink for inkjet recording DIC株式会社 2019-04-05 CN claimed
CN-1151150-C Non-peptide angiotonin II receptor antagon Jw sartan compounds and its synthesizing process and application 王建武 2004-05-26 CN claimed
CN-1369492-A Non-peptide angiotonin II receptor antagon Jw sartan compounds and its synthesizing process and application WANG JIANWU (CN) 2002-09-18 CN claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
EP-0545746-B1 Compositions based on rare earth sulfides, preparation and use thereof RHONE POULENC CHIMIE (FR) 1997-04-23 EP claimed
EP-0580916-B1 N(1) substituted pyrazino [2,3-c]-1,2,6-thiadiazine 2,2-dioxides and their use as pharmaceuticals PRODESFARMA SA (ES) 1997-03-05 EP claimed
US-5319142-A Process for preparing substituted and unsubstituted arylalkylamines HOECHST CELANESE CORPORATION (US) 1994-06-07 US claimed
EP-0580916-A1 N(1) substituted pyrazino 2,3-c -1,2,6-thiadiazine 2,2-dioxides and their use as pharmaceuticals PRODESFARMA, S.A. (ES) 1994-02-02 EP claimed
US-4758312-A Adding colorless electrochemically active compound having positive reduction potential NALCO CHEMICAL COMPANY (US) 1988-07-19 US claimed
US-3966813-A Process for the preparation of 1-(m- and p-hydroxyphenyl)-2-aminoethanol WARNER-LAMBERT COMPANY (US) 1976-06-29 US claimed