Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6718103 | 0.89 | TSHR (0.44) | LMNADNM1PLA2G1BPLA2G2ATSHR | |
| SCHEMBL20835164 | 0.89 | TSHR (0.44) | LMNADNM1PLA2G1BPLA2G2ATSHR | |
| SCHEMBL22096531 | 0.89 | TSHR (0.44) | LMNADNM1PLA2G1BPLA2G2ATSHR | |
| SCHEMBL23437576 | 0.89 | TSHR (0.44) | LMNADNM1PLA2G1BPLA2G2ATSHR | |
| SCHEMBL22401146 | 0.89 | TSHR (0.44) | LMNADNM1PLA2G1BPLA2G2ATSHR | |
| SCHEMBL23437461 | 0.89 | TSHR (0.44) | LMNADNM1PLA2G1BPLA2G2ATSHR | |
| SCHEMBL20882132 | 0.89 | TSHR (0.44) | LMNADNM1PLA2G1BPLA2G2ATSHR | |
| SCHEMBL23437458 | 0.89 | TSHR (0.44) | LMNADNM1PLA2G1BPLA2G2ATSHR | |
| SCHEMBL22401186 | 0.89 | TSHR (0.44) | LMNADNM1PLA2G1BPLA2G2ATSHR | |
| SCHEMBL17199729 | 0.89 | TSHR (0.44) | LMNADNM1PLA2G1BPLA2G2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0143385-B1 | PHOSPHORYLISED GLYCOSIL AMIDES, UREAS, CARBAMATES AND THIOCARBAMATES, METHOD FOR THEIR PREPARATION AND THEIR USE | BAYER AG (DE) | 1989-03-15 | — | — | EP | disclosed |
| US-4686208-A | Phosphorylated glycosyl-amides, -ureas, -carbamates and -thiocarbamates and method of use | BAYER AKTIENGESELLSCHAFT (DE) | 1987-08-11 | — | — | US | disclosed |
| EP-0143385-A2 | Phosphorylised glycosil amides, ureas, carbamates and thiocarbamates, method for their preparation and their use | BAYER AG (DE) | 1985-06-05 | — | — | EP | disclosed |