SCHEMBL17199729

SCHEMBL17199729

CCCCCCCCCC(CCCCCCCCC)N(C)C

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.44
THRB P10828 1/20 0.44
LMNA P02545 1/20 0.44
DNM1 Q05193 5/20 0.43
OPRM1 P35372 1/20 0.42
PLA2G1B P04054 1/20 0.41
PLA2G2A P14555 1/20 0.41
GPR84 Q9NQS5 2/20 0.39
FDPS P14324 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20219104 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL20835164 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL22401146 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL23437458 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL20882132 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL23437576 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL22401186 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL23437461 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL22096531 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL6718103 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111655715-A Stabilized RSV F proteins and uses thereof 默沙东公司 2020-09-11 CN claimed
CN-103167866-B For the novel low molecular weight amount cation lipid of oligonucleotide delivery SIRNA THERAPEUTICS, INC. (US) 2015-09-23 CN claimed
CN-103167866-A Novel low molecular weight cationic lipids for oligonucleotide delivery MERCK SHARP & DOHME 2013-06-19 CN claimed
EP-4630057-A1 LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF Recode Therapeutics, Inc. (US) 2025-10-15 EP disclosed
EP-4590282-A1 LIPID NANOPARTICLE WITH NUCLEIC ACID CARGO NovoArc GmbH (AT) 2025-07-30 EP disclosed
WO-2025137646-A1 GENE EDITING METHODS AND COMPOSITIONS FOR TREATING CYSTIC FIBROSIS RECODE THERAPEUTICS, INC. (US) 2025-06-26 WO disclosed
WO-2025029927-A1 LIPID NANOPARTICLE THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-02-06 WO disclosed
CN-118251498-A Gene constructs for expression of MRNA 基因特力株式会社 2024-06-25 CN disclosed
WO-2024123633-A1 LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF RECODE THERAPEUTICS, INC. (US) 2024-06-13 WO disclosed
CN-117836002-A Hepatitis c virus immunogenic compositions and methods of use thereof 奥罗拉疫苗有限责任公司 2024-04-05 CN disclosed
WO-2024062001-A1 LIPID NANOPARTICLE WITH NUCLEIC ACID CARGO NOVOARC GMBH (AT) 2024-03-28 WO disclosed
CN-112220797-A C/EBP alpha compositions and methods of use 米纳治疗有限公司 2021-01-15 CN disclosed
CN-112236134-A Carotenoid compositions and uses thereof L.E.A.F.控股集团公司 2021-01-15 CN disclosed
EP-2937369-B1 QUATERNARY AMMONIUM SALT-CONTAINING CATALYST FOR DISSOCIATION OF BLOCKING AGENT, AND USE FOR SAID CATALYST TOSOH CORP (JP) 2020-11-11 EP disclosed
CN-107075515-B C/EBP alpha compositions and methods of use 米纳治疗有限公司 2020-10-30 CN disclosed
CN-111655715-A Stabilized RSV F proteins and uses thereof 默沙东公司 2020-09-11 CN disclosed
US-20150344727-A1 QUATERNARY AMMONIUM SALT-CONTAINING CATALYST FOR DISSOCIATION OF BLOCKING AGENT AND USE THEREOF TOSOH CORPORATION (JP) 2015-12-03 US disclosed
EP-2937369-A1 QUATERNARY AMMONIUM SALT-CONTAINING CATALYST FOR DISSOCIATION OF BLOCKING AGENT, AND USE FOR SAID CATALYST Tosoh Corporation (JP) 2015-10-28 EP disclosed
CN-103167866-B For the novel low molecular weight amount cation lipid of oligonucleotide delivery SIRNA THERAPEUTICS, INC. (US) 2015-09-23 CN disclosed
CN-103167866-A Novel low molecular weight cationic lipids for oligonucleotide delivery MERCK SHARP & DOHME 2013-06-19 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150344727-A1 QUATERNARY AMMONIUM SALT-CONTAINING CATALYST FOR DISSOCIATION OF BLOCKING AGENT AND USE THEREOF CA2, KCNMB1, BET1 TSHR 2952/4885THRB 1663/4885LMNA 2087/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.