Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | NEU1 | Q99519 | 1/20 | 0.33 |
| ▸ | NEU2 | Q9Y3R4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzophenone SCHEMBL28904028 | 0.63 | ALDH1A1 (0.64) | ALDH1A1GABRA1GABRB1MAPTPTGS1 | |
| SCHEMBL18220718 | 0.62 | ALDH1A1 (0.37) | ALDH1A1GABRA1GABRB1MAPTPTGS1 | |
| Benzophenone SCHEMBL10904671 | 0.62 | ALDH1A1 (0.61) | ALDH1A1GABRA1GABRB1MAPTPTGS1 | |
| SCHEMBL4242995 | 0.61 | ALDH1A1 (0.48) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL13973388 | 0.60 | ALDH1A1 (0.42) | ALDH1A1GABRA1GABRB1MAPTPTGS1 | |
| Benzophenone SCHEMBL7591788 | 0.60 | ALDH1A1 (0.64) | ALDH1A1GABRA1GABRB1MAPTPTGS1 | |
| Benzophenone SCHEMBL7591787 | 0.60 | ALDH1A1 (0.64) | ALDH1A1GABRA1GABRB1MAPTPTGS1 | |
| Benzophenone SCHEMBL28056782 | 0.60 | ALDH1A1 (0.64) | ALDH1A1GABRA1GABRB1MAPTSMN1; SMN2 | |
| SCHEMBL22175191 | 0.59 | ALDH1A1 (0.45) | ALDH1A1MAPTSMN1; SMN2HPGDKDM4E | |
| SCHEMBL7905164 | 0.59 | ALDH1A1 (0.45) | ALDH1A1GABRA1GABRB1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0012621-B2 | ANALGESIC COMPOSITION COMPRISING ACETAMINOPHEN AS A POTENTIATING AGENT | McNeilab, Inc. (US) | 1989-03-22 | — | — | EP | disclosed |