Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | TSPO | P30536 | 1/20 | 0.34 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10601107 | 0.94 | CYP3A4 (0.35) | CYP3A4HTTSMN1; SMN2P2RX4TP53 | |
| SCHEMBL10595050 | 0.94 | CYP3A4 (0.36) | CYP3A4HTTSMN1; SMN2LMNAMAPT | |
| SCHEMBL10599358 | 0.92 | ALDH1A1 (0.36) | CYP3A4HTTSMN1; SMN2GRM5TP53 | |
| SCHEMBL10599226 | 0.92 | CYP3A4 (0.39) | CYP3A4HTTSMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL10600648 | 0.91 | CNR2 (0.42) | CYP3A4CNR1CNR2 | |
| SCHEMBL10596244 | 0.91 | MAPT (0.38) | CYP3A4SMN1; SMN2CNR1CNR2TP53 | |
| SCHEMBL29982500 | 0.89 | CYP3A4 (0.43) | CYP3A4HTTSMN1; SMN2TP53LMNA | |
| SCHEMBL1727569 | 0.89 | CYP3A4 (0.43) | CYP3A4HTTSMN1; SMN2TP53LMNA | |
| SCHEMBL10634632 | 0.88 | CYP3A4 (0.39) | CYP3A4HTTSMN1; SMN2MAPK1TP53 | |
| SCHEMBL9654429 | 0.88 | CYP3A4 (0.38) | CYP3A4HTTSMN1; SMN2TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4800193-A | ANILINE, INDOLE AND PHTHALEIN DYES; COLORFASTNESS; AROMATIC SOLVENT-SOLUBLE | FUJI PHOTO FILM CO., LTD. (JP) | 1989-01-24 | — | — | US | disclosed |