Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HCN4 | Q9Y3Q4 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10601186 | 0.82 | HCN4 (0.43) | GAASMN1; SMN2HCN4MAPTKCNH2 | |
| SCHEMBL10600128 | 0.80 | HCN4 (0.51) | GAASMN1; SMN2HCN4MAPTKCNH2 | |
| SCHEMBL10601007 | 0.74 | HCN4 (0.56) | GAASMN1; SMN2HCN4MAPTKCNH2 | |
| SCHEMBL10598819 | 0.71 | HCN4 (0.52) | GAASMN1; SMN2HCN4MAPTKCNH2 | |
| SCHEMBL10601090 | 0.70 | HCN4 (0.58) | GAASMN1; SMN2HCN4MAPTKCNH2 | |
| SCHEMBL10976169 | 0.67 | GAA (0.57) | GAASMN1; SMN2HCN4MAPTKCNH2 | |
| Hydrochloric Acid SCHEMBL9666361 | 0.67 | GAA (0.38) | GAASMN1; SMN2HCN4MAPTKCNH2 | |
| Hydrochloric Acid SCHEMBL10601260 | 0.67 | CYP3A4 (0.59) | GAASMN1; SMN2HCN4MAPTKCNH2 | |
| SCHEMBL10599844 | 0.67 | MAPT (0.53) | GAASMN1; SMN2HCN4MAPTKCNH2 | |
| SCHEMBL11096232 | 0.66 | HCN4 (0.67) | GAASMN1; SMN2HCN4MAPTKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0109636-B1 | BENZAZEPINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICAL COMPOUNDS | Dr. Karl Thomae GmbH (DE) | 1989-01-18 | — | — | EP | disclosed |