Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | COMT | P21964 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 2/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP7 | P09237 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29868511 | 0.88 | PARP1 (0.40) | KDM4CCOMTPDE4BTNKS2TGFBR1 | |
| SCHEMBL10462144 | 0.86 | KDM4C (0.42) | KDM4CNR4A1NR4A2NR4A3PTGER1 | |
| SCHEMBL9333910 | 0.86 | COMT (0.44) | COMTMMP1MMP7MMP9MMP8 | |
| SCHEMBL9331046 | 0.85 | KMT2A (0.42) | KDM4CNOTUMRIPK1MMP1MMP7 | |
| SCHEMBL10463753 | 0.84 | COMT (0.43) | COMTMMP1MMP7MMP9MMP8 | |
| SCHEMBL9333422 | 0.84 | MDM2 (0.45) | KDM4CNOTUMCOMTGRIA2GRIA4 | |
| SCHEMBL9330825 | 0.83 | KDM4E (0.44) | KDM4CNOTUMNR4A1NR4A2NR4A3 | |
| SCHEMBL10462925 | 0.78 | KDM4C (0.40) | KDM4CNOTUMNR4A1NR4A2NR4A3 | |
| SCHEMBL9331322 | 0.77 | POLB (0.45) | KDM4CNOTUMKMO | |
| SCHEMBL9331121 | 0.76 | MAPT (0.43) | KDM4CNOTUMNR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0127313-B1 | THE PRODUCTION OF HAPLOID SEED, OF DOUBLED HAPLOIDS AND OF HOMOZYGOUS PLANT LINES THEREFROM | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1989-07-19 | — | — | EP | disclosed |
| EP-0127313-A1 | The production of haploid seed, of doubled haploids and of homozygous plant lines therefrom | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1984-12-05 | — | — | EP | disclosed |