Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.37 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 6/20 | 0.37 |
| ▸ | PPARD | Q03181 | 6/20 | 0.37 |
| ▸ | PPARA | Q07869 | 6/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TLR2 | O60603 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | FABP4 | P15090 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20563911 | 0.98 | CES2 (0.41) | CES2PPARGPPARDPPARAHDAC11 | |
| SCHEMBL4238222 | 0.98 | CES2 (0.41) | CES2PPARGPPARDPPARAHDAC11 | |
| SCHEMBL27521474 | 0.98 | CES2 (0.41) | CES2PPARGPPARDPPARAHDAC11 | |
| SCHEMBL28740418 | 0.94 | TSHR (0.36) | AKR1B1ZDHHC20ZDHHC2PPARGPPARD | |
| SCHEMBL31571624 | 0.92 | TSHR (0.35) | AKR1B1ZDHHC20ZDHHC2PPARGPPARD | |
| SCHEMBL10938229 | 0.79 | CES2 (0.42) | CES2PPARGPPARDPPARAHDAC11 | |
| SCHEMBL20564134 | 0.79 | ABCC4 (0.47) | AKR1B1PPARGPPARDPPARAHDAC11 | |
| SCHEMBL2783596 | 0.78 | ABCC4 (0.50) | PPARGPPARDPPARAHDAC11TSHR | |
| SCHEMBL4166126 | 0.78 | ABCC4 (0.50) | PPARGPPARDPPARAHDAC11TSHR | |
| SCHEMBL3440807 | 0.78 | ABCC4 (0.50) | PPARGPPARDPPARAHDAC11TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0222145-B1 | PROCESS FOR THE PREPARATION OF CARBOXYLIC ACIDS AND THEIR ALKALI METAL SALTS | FIRMENICH SA (CH) | 1989-08-23 | — | — | EP | claimed |
| EP-0222145-B1 | PROCESS FOR THE PREPARATION OF CARBOXYLIC ACIDS AND THEIR ALKALI METAL SALTS | FIRMENICH SA (CH) | 1989-08-23 | — | — | EP | disclosed |
| EP-0222145-A1 | Process for the preparation of carboxylic acids and their alkali metal salts | FIRMENICH SA (CH) | 1987-05-20 | — | — | EP | disclosed |