SCHEMBL10600302

SCHEMBL10600302

C=CCC(C)c1ccccc1-c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
ALDH1A1 P00352 2/20 0.36
MAPK1 P28482 1/20 0.36
CYP2C19 P33261 1/20 0.36
ADRB2 P07550 1/20 0.36
ADRB1 P08588 1/20 0.36
CDC25A P30304 1/20 0.35
CDC25B P30305 1/20 0.35
HTR7 P34969 1/20 0.34
PPARA Q07869 2/20 0.34
PPARG P37231 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
DPP4 P27487 1/20 0.33
PDCD1 Q15116 1/20 0.33
CD274 Q9NZQ7 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TRPA1 O75762 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11490603 0.82 CA12 (0.39) CA12CA1CA2CA9ALDH1A1
SCHEMBL10599254 0.79 SMN1; SMN2 (0.44) ALDH1A1MAPK1CYP2C19ADRB2ADRB1
SCHEMBL11494431 0.78 PPARA (0.35) CA12CA1CA2CA9ALDH1A1
SCHEMBL7568964 0.78 CYP2C19 (0.44) ALDH1A1CYP2C19ADRB2ADRB1HTR7
SCHEMBL11487539 0.78 CA12 (0.33) CA12CA1CA2CA9ALDH1A1
Hydrochloric Acid SCHEMBL2480213 0.77 PDCD1LG2 (0.39) CA12CA1CA2CA9ALDH1A1
SCHEMBL5551237 0.77 TSHR (0.55) CA12CA1CA2CA9ALDH1A1
SCHEMBL9092667 0.76 CA12 (0.40) CA12CA1CA2CA9ALDH1A1
SCHEMBL4637099 0.76 ESR1 (0.42) ALDH1A1CYP2C19ADRB2SMN1; SMN2
SCHEMBL7105245 0.76 CA12 (0.39) CA12CA1CA2CA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0181482-B1 NOVEL ETHYLENE COPOLYMERS Nippon Petrochemicals Co., Ltd. (JP) 1989-01-11 EP disclosed
US-4736007-A WITH UNSATURATED AROMATIC HYDROCARBONS NIPPON PETROCHEMICALS CO., LTD. (JP) 1988-04-05 US disclosed
EP-0181482-A1 Novel ethylene copolymers Nippon Petrochemicals Co., Ltd. (JP) 1986-05-21 EP disclosed