SCHEMBL7568964

SCHEMBL7568964

C=CCC(C(=C)C)c1ccccc1-c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.44
PDCD1 Q15116 1/20 0.34
CD274 Q9NZQ7 1/20 0.34
KMT2A Q03164 2/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
BCL2L1 Q07817 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TRPA1 O75762 1/20 0.33
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
TAS1R3 Q7RTX0 1/20 0.33
TAS1R1 Q7RTX1 1/20 0.33
USP2 O75604 1/20 0.33
HTT P42858 1/20 0.33
KCNQ2 O43526 1/20 0.33
MAPT P10636 1/20 0.33
PPARA Q07869 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
PPARG P37231 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10600302 0.78 CA12 (0.39) CYP2C19PDCD1CD274ALDH1A1TRPA1
Hydrochloric Acid SCHEMBL2480213 0.77 PDCD1LG2 (0.39) CYP2C19CD274KMT2AALDH1A1HPGD
SCHEMBL7561117 0.75 CYP2C19 (0.49) CYP2C19ALDH1A1SMN1; SMN2
SCHEMBL10599254 0.75 SMN1; SMN2 (0.44) CYP2C19KMT2AALDH1A1HPGDBCL2L1
SCHEMBL7438146 0.70 PDCD1LG2 (0.40) CYP2C19CD274KMT2AALDH1A1HPGD
SCHEMBL2474135 0.70 PDCD1LG2 (0.40) CYP2C19CD274KMT2AALDH1A1HPGD
SCHEMBL11122120 0.70 CYP2C19 (0.46) CYP2C19KMT2AUSP2HTTKCNQ2
SCHEMBL9247570 0.69 HSP90AA1 (0.39) KMT2AALDH1A1HPGDBCL2L1HSD17B10
SCHEMBL7105245 0.68 CA12 (0.39) PDCD1CD274ALDH1A1HPGDBCL2L1
SCHEMBL8717008 0.68 ALDH1A1 (0.40) PDCD1CD274KMT2AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002079140-A1 NOVEL POLYVALENT CARBOXYLIC ACID ESTERS AND THEIR USE IN PLASTIC LENS COMPOSITIONS SHOWA DENKO K. K. (JP) 2002-10-10 WO disclosed