Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GJB2 | P29033 | 4/20 | 0.43 |
| ▸ | FGF1 | P05230 | 3/20 | 0.39 |
| ▸ | FGF2 | P09038 | 3/20 | 0.39 |
| ▸ | VEGFA | P15692 | 3/20 | 0.39 |
| ▸ | HPSE | Q9Y251 | 3/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 2/20 | 0.38 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.37 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.37 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.37 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10600399 | 1.00 | GJB2 (0.43) | GJB2FGF1FGF2VEGFAHPSE | |
| SCHEMBL15948823 | 0.87 | GJB2 (0.42) | GJB2FGF1FGF2VEGFAHPSE | |
| SCHEMBL16576214 | 0.87 | GJB2 (0.42) | GJB2FGF1FGF2VEGFAHPSE | |
| SCHEMBL10154158 | 0.87 | GJB2 (0.42) | GJB2FGF1FGF2VEGFAHPSE | |
| SCHEMBL15481866 | 0.87 | GJB2 (0.42) | GJB2FGF1FGF2VEGFAHPSE | |
| SCHEMBL11666504 | 0.86 | GJB2 (0.46) | GJB2FGF1FGF2VEGFAHPSE | |
| SCHEMBL5985701 | 0.86 | GJB2 (0.46) | GJB2FGF1FGF2VEGFAHPSE | |
| SCHEMBL11666500 | 0.86 | GJB2 (0.46) | GJB2FGF1FGF2VEGFAHPSE | |
| SCHEMBL5985705 | 0.86 | GJB2 (0.46) | GJB2FGF1FGF2VEGFAHPSE | |
| SCHEMBL2059653 | 0.84 | SSTR1 (0.46) | GJB2FGF1FGF2VEGFAHPSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0145978-B1 | NUCLEOSIDE PROCESS | Bristol-Myers Company (US) | 1989-04-19 | — | — | EP | claimed |