Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.68 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10603954 | 0.88 | ALOX5 (0.56) | ALOX5NR1I2KMT2AKIF11KDM4E | |
| SCHEMBL10601878 | 0.86 | ALOX5 (0.69) | ALOX5NR1I2ALDH1A1MAPTKMT2A | |
| SCHEMBL10601936 | 0.86 | ALOX5 (0.69) | ALOX5NR1I2ALDH1A1NPC1MAPT | |
| SCHEMBL10601766 | 0.83 | ALOX5 (0.66) | ALOX5NR1I2ALDH1A1NPC1MAPT | |
| SCHEMBL10600159 | 0.83 | ALOX5 (0.66) | ALOX5NR1I2KIF11KEAP1F2 | |
| SCHEMBL10602830 | 0.83 | ALOX5 (0.66) | ALOX5NR1I2ALDH1A1NPC1MAPT | |
| SCHEMBL10459471 | 0.82 | ALOX5 (0.64) | ALOX5NR1I2ALDH1A1MAPTKIF11 | |
| SCHEMBL8235035 | 0.81 | F2 (0.58) | ALDH1A1KIF11KEAP1NFE2L2F2 | |
| SCHEMBL10459430 | 0.81 | ALOX5 (1.00) | ALOX5NR1I2ALDH1A1NPC1MAPT | |
| SCHEMBL10603945 | 0.81 | ALOX5 (0.63) | ALOX5NR1I2ALDH1A1MAPTKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0173279-B1 | 2-(3,5-DIALKYL-4-HYDROXYPHENYL)INDOLE DERIVATIVES | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1989-08-23 | — | — | EP | disclosed |
| US-4695581-A | LIPOXYGENASE INHIBITOR | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1987-09-22 | — | — | US | disclosed |
| EP-0173279-A1 | 2-(3,5-Dialkyl-4-hydroxyphenyl)indole derivatives | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1986-03-05 | — | — | EP | disclosed |