Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10601865 | 0.85 | NR1H2 (0.32) | NR1H2NR1H3 | |
| SCHEMBL9559598 | 0.84 | NR1H2 (0.33) | NR1H2NR1H3SMN1; SMN2 | |
| SCHEMBL9559662 | 0.83 | — | — | |
| SCHEMBL9559561 | 0.82 | NR1H2 (0.34) | NR1H2NR1H3 | |
| SCHEMBL9559547 | 0.82 | NR1H2 (0.34) | NR1H2NR1H3 | |
| SCHEMBL11320711 | 0.80 | ALDH1A1 (0.31) | — | |
| SCHEMBL9559534 | 0.78 | — | — | |
| SCHEMBL9559528 | 0.77 | NR1H2 (0.31) | NR1H2NR1H3 | |
| SCHEMBL9559525 | 0.76 | ADORA1 (0.31) | — | |
| SCHEMBL9559584 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0148026-B1 | FUNGICIDAL IMIDAZOLES AND TRIAZOLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-04-19 | — | — | EP | disclosed |
| US-4530922-A | Fungicidal imidazoles and triazoles containing silicon | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-07-23 | — | — | US | disclosed |
| EP-0148026-A2 | Fungicidal imidazoles and triazoles | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-07-10 | — | — | EP | disclosed |