Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 5/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 3/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | F12 | P00748 | 1/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.43 |
| ▸ | F3 | P13726 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | C1S | P09871 | 1/20 | 0.43 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.43 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.43 |
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12648649 | 0.82 | CYP1A2 (0.59) | CYP1A2CYP2D6MEN1KMT2ACYP2C19 | |
| SCHEMBL715285 | 0.82 | CYP1A2 (0.59) | CYP1A2CYP2D6MEN1KMT2ACYP2C19 | |
| SCHEMBL29410187 | 0.82 | CYP1A2 (0.59) | CYP1A2CYP2D6MEN1KMT2ACYP2C19 | |
| SCHEMBL6011852 | 0.77 | MEN1 (0.73) | NQO2CYP1A2ITGB3ITGA2BF2 | |
| SCHEMBL24208279 | 0.76 | BLM (0.53) | CYP1A2CYP2D6PKMMEN1KMT2A | |
| SCHEMBL11510852 | 0.76 | CYP1A2 (0.54) | CYP1A2CYP2D6MEN1KMT2ALMNA | |
| SCHEMBL5427934 | 0.76 | BLM (0.53) | CYP1A2CYP2D6PKMMEN1KMT2A | |
| SCHEMBL3620340 | 0.76 | CYP1A2 (0.54) | CYP1A2CYP2D6MEN1KMT2ALMNA | |
| SCHEMBL23706076 | 0.76 | BLM (0.53) | CYP1A2CYP2D6PKMMEN1KMT2A | |
| SCHEMBL3563313 | 0.76 | CYP1A2 (0.50) | CYP1A2CYP2D6PKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0118280-B1 | ENZYME INHIBITION | Aktiebolaget Hässle (SE) | 1989-07-12 | — | — | EP | disclosed |