Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NQO1 | P15559 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 5/20 | 0.47 |
| ▸ | ALPI | P09923 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10953976 | 0.89 | NQO1 (0.47) | HSD17B3KDM4EALDH1A1HPGDGAA | |
| SCHEMBL28091488 | 0.84 | NQO1 (0.53) | HSD17B3NQO1LMNAARCA12 | |
| SCHEMBL10602309 | 0.80 | NQO1 (0.49) | KDM4EALDH1A1HPGDGAAHTT | |
| SCHEMBL10792497 | 0.80 | HSD17B3 (0.77) | HSD17B3KDM4EALDH1A1HPGDGAA | |
| SCHEMBL10600424 | 0.78 | NQO1 (0.54) | KDM4EALDH1A1TDP1HTTNQO1 | |
| SCHEMBL3078189 | 0.76 | HSD17B3 (0.57) | HSD17B3KDM4EALDH1A1HPGDGAA | |
| SCHEMBL15750030 | 0.75 | GABRP (0.41) | KDM4EALDH1A1GAAHTTNQO1 | |
| SCHEMBL27752820 | 0.75 | HSD17B3 (0.60) | HSD17B3KDM4EALDH1A1HPGDGAA | |
| SCHEMBL3079436 | 0.75 | ERAP1 (0.58) | KDM4EALDH1A1NQO1ARCA1 | |
| SCHEMBL31331868 | 0.75 | HSD17B3 (0.56) | HSD17B3KDM4EALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0185319-B1 | FLUORO COUMARINS AS ANTILYMPHOEDEMA AGENTS | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1989-09-06 | — | — | EP | claimed |
| EP-0185319-B1 | FLUORO COUMARINS AS ANTILYMPHOEDEMA AGENTS | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1989-09-06 | — | — | EP | disclosed |
| US-4749798-A | ANTIINFLAMMATORY, ANTISWELLING | BOEHRINGER BIOCHEMIA ROBIN SPA (IT) | 1988-06-07 | — | — | US | disclosed |
| EP-0185319-A2 | Fluoro coumarins as antilymphoedema agents | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1986-06-25 | — | — | EP | disclosed |