Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.43 |
| ▸ | RELA | Q04206 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10602210 | 0.98 | RARB (0.52) | RARBRAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL8332757 | 0.95 | RARB (0.59) | RARBRAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL10602751 | 0.94 | RARB (0.62) | RARBRAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL10603518 | 0.94 | RARB (0.58) | RARBRAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL10605932 | 0.93 | RARB (0.60) | RARBRAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL9351455 | 0.90 | CTSS (0.46) | RARBRAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL10872765 | 0.89 | RARB (0.54) | RARBRAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL9348005 | 0.89 | CTSS (0.45) | RARBRAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL10611816 | 0.88 | MAPT (0.59) | RARBRAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL27471980 | 0.86 | RARB (0.55) | RARBRAB9ASMN1; SMN2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0193191-B1 | PYRIMIDINE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CONTAINING SAME | Chisso Corporation (JP) | 1989-09-13 | — | — | EP | disclosed |
| US-4684476-A | LOW VOLTAGE | CHISSO CORPORATION (JP) | 1987-08-04 | — | — | US | disclosed |