SCHEMBL10604263

SCHEMBL10604263

c1ccc(N(Cn2ccnn2)c2ccccc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 20/20 0.55
CYP1A1 P04798 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18492603 0.85 CYP19A1 (0.45) CYP19A1CYP1A1
SCHEMBL10600883 0.85 CYP19A1 (0.55) CYP19A1CYP1A1
SCHEMBL18488942 0.83 CYP19A1 (0.43) CYP19A1
SCHEMBL18488945 0.81 CYP19A1 (0.41) CYP19A1
SCHEMBL18488934 0.81 CYP19A1 (0.41) CYP19A1
SCHEMBL18492601 0.77 CYP19A1 (0.39) CYP19A1
SCHEMBL5207910 0.76 CYP19A1 (0.45) CYP19A1CYP1A1
SCHEMBL18488926 0.75 NISCH (0.38) CYP19A1
SCHEMBL18488937 0.73 ESR1 (0.41)
SCHEMBL155247 0.71 CYP19A1 (1.00) CYP19A1CYP1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0160620-B1 METAL DEACTIVATORS CIBA-GEIGY AG (CH) 1989-09-13 EP claimed
EP-0160620-B1 METAL DEACTIVATORS CIBA-GEIGY AG (CH) 1989-09-13 EP disclosed