Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 19/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10604263 | 0.76 | CYP19A1 (0.55) | CYP19A1CYP1A1 | |
| SCHEMBL10600883 | 0.76 | CYP19A1 (0.55) | CYP19A1CYP1A1 | |
| SCHEMBL10912473 | 0.71 | CYP19A1 (0.38) | CYP19A1CYP1A1 | |
| SCHEMBL10526462 | 0.69 | ALDH1A1 (0.52) | — | |
| SCHEMBL27457628 | 0.68 | ALDH1A1 (0.50) | — | |
| SCHEMBL28647892 | 0.68 | ALDH1A1 (0.50) | — | |
| SCHEMBL20180510 | 0.67 | TP53 (0.49) | — | |
| SCHEMBL6763673 | 0.67 | CYP19A1 (0.59) | CYP19A1CYP1A1 | |
| SCHEMBL1499131 | 0.67 | ALDH1A1 (0.48) | — | |
| SCHEMBL340272 | 0.67 | ALDH1A1 (0.70) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1804785-A2 | DIARYL UREAS AS CB1 ANTAGONISTS | NEUROGEN CORPORATION (US) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006049941-A2 | DIARYL UREAS AS CB1 ANTAGONISTS | NEUROGEN CORPORATION (US) | 2006-05-11 | — | — | WO | disclosed |