Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PREP | P48147 | 3/20 | 0.42 |
| ▸ | FAP | Q12884 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 3/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 2/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10604749 | 1.00 | KMT2A (0.43) | KMT2APREPFAPCTSKCTSL | |
| SCHEMBL10605519 | 1.00 | KMT2A (0.43) | KMT2APREPFAPCTSKCTSL | |
| SCHEMBL8253773 | 0.87 | ELANE (0.41) | CTSKCTSLCTSBCMA1ACE | |
| SCHEMBL25906663 | 0.87 | ELANE (0.41) | CTSKCTSLCTSBCMA1ACE | |
| SCHEMBL10604644 | 0.86 | ACE (0.42) | CTSKCTSLCTSBACEITGB3 | |
| SCHEMBL10604631 | 0.86 | ACE (0.42) | CTSKCTSLCTSBACEITGB3 | |
| SCHEMBL12335495 | 0.83 | CACNA1B (0.41) | CTSKCMA1ACEKLK5ITGB3 | |
| SCHEMBL28649912 | 0.82 | PREP (0.45) | KMT2APREPFAPCTSKCTSL | |
| SCHEMBL18215150 | 0.82 | PREP (0.45) | KMT2APREPFAPCTSKCTSL | |
| SCHEMBL26708538 | 0.82 | PREP (0.45) | KMT2APREPFAPCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021188696-A1 | STAT DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2021-09-23 | — | — | WO | disclosed |
| EP-3145944-B1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2021-05-05 | — | — | EP | disclosed |
| EP-0154353-B1 | AN ANTI-AMNESTIC AGENT | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1989-11-15 | — | — | EP | disclosed |
| US-4687778-A | Anti-amnestic agent | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1987-08-18 | — | — | US | disclosed |
| EP-0154353-A2 | An anti-amnestic agent | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1985-09-11 | — | — | EP | disclosed |