Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.40 |
| ▸ | CTSK | P43235 | 4/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10604631 | 1.00 | ACE (0.42) | ACEF2PRSS1HDAC8ITGB3 | |
| SCHEMBL12335495 | 0.87 | CACNA1B (0.41) | ACEF2PRSS1ITGB3ITGA2B | |
| SCHEMBL26217524 | 0.86 | ITGB3 (0.42) | ACEF2PRSS1ITGB3ITGA2B | |
| SCHEMBL10604749 | 0.86 | KMT2A (0.43) | ACEHDAC8ITGB3ITGA2BCTSK | |
| SCHEMBL10604758 | 0.86 | KMT2A (0.43) | ACEHDAC8ITGB3ITGA2BCTSK | |
| SCHEMBL10605519 | 0.86 | KMT2A (0.43) | ACEHDAC8ITGB3ITGA2BCTSK | |
| SCHEMBL25906663 | 0.84 | ELANE (0.41) | ACECTSKCTSLCTSB | |
| SCHEMBL8253773 | 0.84 | ELANE (0.41) | ACECTSKCTSLCTSB | |
| SCHEMBL22070276 | 0.83 | ACE (0.57) | ACEF2PRSS1 | |
| SCHEMBL22070275 | 0.83 | ACE (0.57) | ACEF2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154353-B1 | AN ANTI-AMNESTIC AGENT | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1989-11-15 | — | — | EP | disclosed |
| US-4687778-A | Anti-amnestic agent | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1987-08-18 | — | — | US | disclosed |
| EP-0154353-A2 | An anti-amnestic agent | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1985-09-11 | — | — | EP | disclosed |