Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 8/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 7/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.33 |
| ▸ | GALR3 | O60755 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.33 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1370015 | 0.98 | SMN1; SMN2 (0.44) | SMN1; SMN2CHRM1CHRM3CHRM2CHRM4 | |
| Zinc Ion SCHEMBL10604225 | 0.97 | SMN1; SMN2 (0.43) | SMN1; SMN2CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL10602664 | 0.97 | SMN1; SMN2 (0.43) | SMN1; SMN2CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL10604517 | 0.97 | SMN1; SMN2 (0.43) | SMN1; SMN2CHRM1CHRM3CHRM2CHRM4 | |
| Propylene Glycol SCHEMBL8861293 | 0.95 | SMN1; SMN2 (0.42) | SMN1; SMN2CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL5357432 | 0.87 | SMN1; SMN2 (0.37) | SMN1; SMN2CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL159440 | 0.76 | SMN1; SMN2 (0.50) | SMN1; SMN2CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL26661989 | 0.76 | SMN1; SMN2 (0.50) | SMN1; SMN2CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL28229216 | 0.76 | SMN1; SMN2 (0.50) | SMN1; SMN2CHRM1CHRM3CHRM2CHRM4 | |
| Iodide SCHEMBL10581935 | 0.75 | SMN1; SMN2 (0.49) | SMN1; SMN2CHRM1CHRM3CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0186803-B1 | DIACYLDERIVATIVES OF GLYCERYLPHOSPHORYLCHOLINE HAVING THERAPEUTICAL ACTIVITY, A PROCESS FOR THEIR PREPARATION AND RELATED PHARMACEUTICAL COMPOSITIONS | NEOPHARMED S.p.A. (IT) | 1989-09-20 | — | — | EP | claimed |
| US-4699901-A | Diacyl derivatives of glycerylphosphorylcholine, their preparation, and antihyperlipidemic compositions | NEOPHARMED SPA (IT) | 1987-10-13 | — | — | US | claimed |
| EP-0186803-A2 | Diacylderivatives of glycerylphosphorylcholine having therapeutical activity, a process for their preparation and related pharmaceutical compositions | NEOPHARMED S.p.A. (IT) | 1986-07-09 | — | — | EP | claimed |